Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac
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Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinPhospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signalingPhosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cellsEssential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.A comprehensive pathway map of epidermal growth factor receptor signalingMLK3 Signaling in Cancer InvasionThe dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patternsTyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangementsLocal phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domainThe homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreadingAn active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandEndogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors.DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent mannerChlamydial entry involves TARP binding of guanine nucleotide exchange factors.Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer.Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture.Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling.Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity.Expression and localization of SWAP-70 in human fetomaternal interface and placenta during tubal pregnancy and normal placentation.RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac.Rac signaling in breast cancer: a tale of GEFs and GAPs.Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migrationGalectin-3- and phospho-caveolin-1-dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells.Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer.Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.Inhibition and termination of physiological responses by GTPase activating proteins.Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivoEphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer.Regulatory mechanisms of EGFR signalling during Drosophila eye development.Rationalizing Rac1 and RhoA GTPase signaling: A mathematical approach.Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.VAV2 regulates epidermal growth factor receptor endocytosis and degradation.Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.
P2860
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P2860
Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 14 February 2003)
@en
vedecký článok (publikovaný 2003/02/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/14)
@nl
наукова стаття, опублікована в лютому 2003
@uk
name
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@ast
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@en
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@nl
type
label
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@ast
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@en
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@nl
prefLabel
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@ast
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@en
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@nl
P2093
P3181
P356
P1476
Mechanism of epidermal growth ...... eotide exchange factor for Rac
@en
P2093
András Bauer
András Illés
Anna Faragó
László Buday
Petra Bauer
Péter Tamás
Zita Solti
P304
P3181
P356
10.1074/JBC.M207555200
P407
P577
2003-02-14T00:00:00Z