Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
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Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1Vav family exchange factors: an integrated regulatory and functional viewDistinct predictive performance of Rac1 and Cdc42 in cell migrationHow cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityTiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowthAn essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cellsDissecting activation of the PAK1 kinase at protrusions in living cells.Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesisPotassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation.R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory networkRapid turnover rate of phosphoinositides at the front of migrating MDCK cells.Vav3-deficient mice exhibit a transient delay in cerebellar developmentPhosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cellsCdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neuronsQuantification of local morphodynamics and local GTPase activity by edge evolution tracking.Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis.Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensorModelling cell polarization driven by synthetic spatially graded Rac activationA mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection.Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structureTransport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity.Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-cateninTelencephalin protects PAJU cells from amyloid beta protein-induced apoptosis by activating the ezrin/radixin/moesin protein family/phosphatidylinositol-3-kinase/protein kinase B pathway.Intracellular control of developmental and regenerative axon growth.LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic deliveryPhosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cellRap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization.Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosisMembrane organization and dynamics in cell polarity.Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brainThe role of small GTPases in neuronal morphogenesis and polarity.Cytoskeletal and signaling mechanisms of neurite formation.Control of neurite outgrowth by RhoA inactivation.The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissuesCrosstalk of cell polarity signaling pathways.Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs.
P2860
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P248
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P2860
Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Local phosphatidylinositol 3,4 ...... h factor-stimulated PC12 cells
@nl
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@ast
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@en
type
label
Local phosphatidylinositol 3,4 ...... h factor-stimulated PC12 cells
@nl
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@ast
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@en
prefLabel
Local phosphatidylinositol 3,4 ...... h factor-stimulated PC12 cells
@nl
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@ast
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@en
P2093
P2860
P921
P356
P1476
Local phosphatidylinositol 3,4 ...... factor-stimulated PC12 cells.
@en
P2093
Kazuhiro Aoki
Keiko Fujikawa
Michiyuki Matsuda
Takeshi Nakamura
P2860
P304
P356
10.1091/MBC.E04-10-0904
P577
2005-02-23T00:00:00Z