Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival
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Insulin in central nervous system: more than just a peripheral hormoneThe critical role of Akt in cardiovascular functionAkt2 negatively regulates assembly of the POSH-MLK-JNK signaling complexCross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediatorsCritical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injuryInhibition of MLK3-MKK4/7-JNK1/2 pathway by Akt1 in exogenous estrogen-induced neuroprotection against transient global cerebral ischemia by a non-genomic mechanism in male ratsMLK3 regulates fMLP-stimulated neutrophil motility.Regulation of the Pro-apoptotic scaffolding protein POSH by Akt.Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3.TRAF2-MLK3 interaction is essential for TNF-alpha-induced MLK3 activation.Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesisNovel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burnEstrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells.Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death.Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disordersUses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.Mixed lineage kinase 3 modulates β-catenin signaling in cancer cellsPI3K/Akt and apoptosis: size matters.Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo.Bad as a converging signaling molecule between survival PI3-K/Akt and death JNK in neurons after transient focal cerebral ischemia in ratsPAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulationMixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular functionMetabolic stress signaling mediated by mixed-lineage kinases.Human Epidermal Growth Factor Receptor 2 (HER2) Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival.Impaired apoptosis and immune senescence - cause or effect?Angiogenesis, immune system and growth factors: new targets in colorectal cancer therapy.Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1-MEK-JNK signal transduction pathway during metabolic oxidative stress: a negative feedback loop.From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy.Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative diseaseMixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function.The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complexTargeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts.Mixed Lineage Kinase-c-Jun N-Terminal Kinase Axis: A Potential Therapeutic Target in Cancer.Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell deathMitochondrial energy metabolism and redox signaling in brain aging and neurodegenerationGlycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging.
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P2860
Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival
description
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 7 February 2003)
@en
vedecký článok (publikovaný 2003/02/07)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/02/07)
@nl
наукова стаття, опублікована в лютому 2003
@uk
name
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@ast
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@en
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@nl
type
label
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@ast
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@en
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@nl
prefLabel
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@ast
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@en
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@nl
P2093
P2860
P356
P1476
Negative regulation of mixed l ...... e B/AKT leads to cell survival
@en
P2093
Anamika Pradeep
Basabi Rana
Chanakya N Kundu
Chandan Sharma
Manoj K Barthwal
Pradeep Sathyanarayana
P2860
P304
P356
10.1074/JBC.M211598200
P407
P577
2003-02-07T00:00:00Z