The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
about
Osteoclasts are active in bone forming metastases of prostate cancer patientsA novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast functionFGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and developmentCCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cellsThe level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signatureMesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiationModulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?Immunogenic targets for specific immunotherapy in multiple myelomaGenetic polymorphism in extracellular regulators of Wnt signaling pathwayManagement of endocrine disease: Secondary osteoporosis: pathophysiology and managementDiagnosis and treatment of bone disease in multiple myeloma: spotlight on spinal involvementImmunotherapy strategies for multiple myeloma: the present and the futureTargeting tumor-stromal interactions in bone metastasisThe role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasisLRP5 and LRP6 in development and diseaseNuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancerNovel biological markers of bone: from bone metabolism to bone physiologyThe insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potentialMechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone RemodelingEpigenetic dysregulation of Wnt signaling pathway in multiple myelomaPotential role for therapies targeting DKK1, LRP5, and serotonin in the treatment of osteoporosisRecognizing and treating secondary osteoporosisWhere Wnts went: the exploding field of Lrp5 and Lrp6 signaling in boneTgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growthComputational modeling of interactions between multiple myeloma and the bone microenvironmentWIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signalingDkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesisIncreased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1Multi-Scale Agent-Based Multiple Myeloma Cancer Modeling and the Related Study of the Balance between Osteoclasts and OsteoblastsDickkopf-1 regulates bone formation in young growing rodents and upon traumatic injuryPTH stimulates bone formation in mice deficient in Lrp5Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new boneInhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult ratsDickkopf homolog 1 mediates endothelin-1-stimulated new bone formationAnalysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancyAndrogen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms.False discovery rate control in two-stage designs.Macrophages modulate adult zebrafish tail fin regeneration.Multi-task feature selection in microarray data by binary integer programming.Increased Dickkopf-1 in Recent-onset Rheumatoid Arthritis is a New Biomarker of Structural Severity. Data from the ESPOIR Cohort
P2860
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P2860
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@ast
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@en
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@nl
type
label
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@ast
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@en
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@nl
prefLabel
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@ast
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@en
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@nl
P2093
P3181
P356
P1476
The role of the Wnt-signaling ...... ic lesions in multiple myeloma
@en
P2093
Erik Rasmussen
Erming Tian
Fenghuang Zhan
John D Shaughnessy
Ronald Walker
P304
P3181
P356
10.1056/NEJMOA030847
P407
P577
2003-12-25T00:00:00Z