WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
about
Development of anticancer agents targeting the Wnt/β-catenin signalingStem cell guidance through the mechanistic target of rapamycinStructural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical TrialsNovel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic diseaseHuman Sarcoma growth is sensitive to small-molecule mediated AXIN stabilization.ABC transporters in CSCs membranes as a novel target for treating tumor relapse.Families of microRNAs Expressed in Clusters Regulate Cell Signaling in Cervical Cancer.Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.New insights into the regulation of Axin function in canonical Wnt signaling pathway.Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera).Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.Tankyrases as drug targets.Regulation of Wnt/β-catenin signaling by posttranslational modificationsTankyrases: structure, function and therapeutic implications in cancer.Recent advances in the structure-based rational design of TNKSIs.Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders.lnc-β-Catm elicits EZH2-dependent β-catenin stabilization and sustains liver CSC self-renewal.The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines.Targeting Tankyrase to Fight WNT-dependent Tumours.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin PathwayIdentification of Novel Target for Osteosarcoma by Network Analysis
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P2860
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@ast
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@en
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@nl
type
label
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@ast
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@en
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@nl
prefLabel
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@ast
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@en
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@nl
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WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
@en
P2093
Katherine A Bosch
Kathryn C Davidson
Kerry Fowler
Nathan D Camp
Nicholas C Robin
Richard G James
Russell J Taylor
Timothy J Martins
Travis L Biechele
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P304
P3181
P356
10.1371/JOURNAL.PONE.0050457
P407
P577
2012-01-01T00:00:00Z