Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma - Test2 - elhamkhani - TriplyDB

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

http://www.wikidata.org/entity/Q28237604

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A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma Molecular subgroups of medulloblastoma: the current consensus Dissecting the genomic complexity underlying medulloblastoma The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors Significance and therapeutic value of miRNAs in embryonal neural tumors Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance Small-Molecule Ligands of Methyl-Lysine Binding Proteins A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer Subgroup-specific structural variation across 1,000 medulloblastoma genomes Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome The genetic landscape of the childhood cancer medulloblastoma G-protein coupled receptor expression patterns delineate medulloblastoma subgroups H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma.JISTIC: identification of significant targets in cancer.Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins.Loss, mutation and deregulation of L3MBTL4 in breast cancers.Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas.Identification and functional analysis of 9p24 amplified genes in human breast cancer.Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1.Epigenomic alterations define lethal CIMP-positive ependymomas of infancy Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.

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P2860

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

http://www.wikidata.org/entity/Q28237604

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Multiple recurrent genetic eve ...... methylation in medulloblastoma

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Multiple recurrent genetic eve ...... methylation in medulloblastoma

@en

Multiple recurrent genetic eve ...... methylation in medulloblastoma

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type

label

Multiple recurrent genetic eve ...... methylation in medulloblastoma

@ast

Multiple recurrent genetic eve ...... methylation in medulloblastoma

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Multiple recurrent genetic eve ...... methylation in medulloblastoma

@nl

prefLabel

Multiple recurrent genetic eve ...... methylation in medulloblastoma

@ast

Multiple recurrent genetic eve ...... methylation in medulloblastoma

@en

Multiple recurrent genetic eve ...... methylation in medulloblastoma

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Nature Genetics

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Multiple recurrent genetic eve ...... methylation in medulloblastoma

@en

P2093

Adrian Dubuc

http://www.w3.org/2001/XMLSchema#string

Boleslaw Lach

http://www.w3.org/2001/XMLSchema#string

Carlos G Carlotti

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Darrell Bigner

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David W Ellison

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Frederick Boop

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Ian F Pollack

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J Sunil Rao

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James T Rutka

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Jessica McLeod

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P2860

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

Characterizing the cancer genome in lung adenocarcinoma.

Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis

Histone H3 specific acetyltransferases are essential for cell cycle progression.

Coordinated histone modifications mediated by a CtBP co-repressor complex

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

Medulloblastoma: developmental mechanisms out of control

P2888

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465-72

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scholarly article

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3023756

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10.1038/NG.336

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4

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41

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Paul N. Kongkham

Stephen W. Scherer

Charles G Eberhart

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2009-04-01T00:00:00Z

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1035880217

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19270706

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medulloblastoma

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4454371

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