Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice. - Test2 - elhamkhani - TriplyDB

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

http://www.wikidata.org/entity/Q34107271

about

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation H3K9me2/3 binding of the MBT domain protein LIN-61 is essential for Caenorhabditis elegans vulva development The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity.Cognition and mood-related behaviors in L3mbtl1 null mutant mice.SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cells The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.Loss of BAP1 function leads to EZH2-dependent transformation.Simultaneous hyper- and hypomethylation at imprinted loci in a subset of patients with GNAS epimutations underlies a complex and different mechanism of multilocus methylation defect in pseudohypoparathyroidism type 1b.Essential Role for Polycomb Group Protein Pcgf6 in Embryonic Stem Cell Maintenance and a Noncanonical Polycomb Repressive Complex 1 (PRC1) Integrity.

P2860

Q24306486-8B616AC9-8E07-4B98-A088-E3E9319FD4E4 Q26823191-55B48E70-0032-4E45-B2FC-25FE39CAA43E Q28302907-8AB893B3-57C1-4658-BD00-80A5D6A34C6E Q28477443-D7344E06-AFE9-45F7-A792-082AE12F299F Q28594836-5ABF602D-FC65-415E-8F91-943F14C2A711 Q33569847-66229266-3D85-4ED4-81C0-356FD52D4DED Q34450058-35A823F2-0F27-4AB6-A3E3-DD2997685FCC Q34647591-F7FB7E8F-6259-4715-BCCE-ADC1757C438E Q35303623-C8CBEE31-78B3-4B63-BBAA-521F51B75792 Q35338785-63695409-77B3-40E9-BE5A-5D96F0247FD0 Q36670976-C3DAC904-C7C9-4F03-AC30-8075D274473C Q36793471-B37D197F-8F85-478E-8A26-11C82F00B378 Q37346666-97DDF18E-782D-46A9-86C3-ED1C69782DEF Q37498531-27F261EF-B718-4881-A341-7B2651F13CFD Q38830247-A78D67D6-91A5-4F13-9961-BEFDEFE94436 Q51014930-A44B4E17-63FB-4C1E-B6B7-ADAE44A5A855 Q51219859-3B973DC8-EBDC-4CB6-BF63-94493E4136B9

P2860

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

http://www.wikidata.org/entity/Q34107271

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@ast

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@en

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@nl

type

label

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@ast

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@en

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@nl

prefLabel

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@ast

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@en

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@nl

P1433

Q34107271-AEE1A37C-88ED-4E8E-B7DF-C23E4026918D

P1476

Q34107271-7CA6A587-2700-4395-9FD6-94BC7E99EE43

P2093

Q34107271-0CDBC84D-D192-4166-9BFC-9313DADF7D3B

Q34107271-2BB78B20-7B18-437C-A037-5617E1FBA77A

Q34107271-4937C748-EC74-440F-AC10-A67A9E47BD08

Q34107271-76C9456E-327A-4283-B28A-F5AB12A545F8

Q34107271-9E68E480-2AB6-4FA5-A18C-6C059F1474CD

Q34107271-B4AC3B01-FB0E-4208-83A1-3A41A73559F1

Q34107271-D685DA70-835D-4506-9560-C70F460E3BD4

P2860

Q34107271-0D1392E1-D612-4808-9F51-57B4DDFAA9CD

Q34107271-1A48D56B-780A-4A18-91B7-3AC23DA94D56

Q34107271-1C96D3B8-1AE2-4510-80F1-E8CA1DC8AB71

Q34107271-217A110F-D063-42C0-9B24-B51AE6A48398

Q34107271-304A11B5-5505-46DD-A0BA-1A1F4CF3EE48

Q34107271-31BB14DB-E260-403F-A1AF-DAB7D3EACC8C

Q34107271-340E9BD7-B45C-4161-83DC-C7C14948B488

Q34107271-347D8858-783F-4366-8188-35D95535ECE3

Q34107271-3A9D744C-5AD7-4091-BAC9-7F8A844F03F2

Q34107271-3B07BAD5-7706-42BB-81A2-3BBE00750E4F

P304

Q34107271-5277733F-5870-4B11-A01F-0F2975D91566

P31

Q34107271-E2360264-E9A3-43B9-AEC6-F1FAD16CCE27

P356

Q34107271-38349982-7F6A-46FD-86D3-41E2345F99E5

P407

Q34107271-1F0624A3-F1A1-4E8A-9A9C-BF1F469C6D5E

P433

Q34107271-0BC9E515-BE09-4A7D-A442-A56A505D57D0

P478

Q34107271-35FE2774-2DC0-4B4B-BC7C-4C7C58066D9B

P577

Q34107271-87AA80C3-040D-41CA-B8A9-F8548F821515

P698

Q34107271-69B77D20-5DA5-4F13-A517-960A3C5B1DBD

P932

Q34107271-36BEE267-C856-4851-8822-FA4BA4C53554

P356

JBC.M110.115410

P1433

Journal of Biological Chemistry

P1476

Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice.

@en

P2093

Denille Van Buren

http://www.w3.org/2001/XMLSchema#string

Hanno Hock

http://www.w3.org/2001/XMLSchema#string

Hsien-Sung Huang

http://www.w3.org/2001/XMLSchema#string

Jinzhong Qin

http://www.w3.org/2001/XMLSchema#string

Lei Zhong

http://www.w3.org/2001/XMLSchema#string

Raul Mostoslavsky

http://www.w3.org/2001/XMLSchema#string

Schahram Akbarian

http://www.w3.org/2001/XMLSchema#string

P2860

Structural studies of a four-MBT repeat protein MBTD1

A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes

Identification of SCML2, a second human gene homologous to the Drosophila sex comb on midleg (Scm): A new gene cluster on Xp22

The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34

The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells

L3MBTL1, a histone-methylation-dependent chromatin lock

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt

P304

27767-27775

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M110.115410

http://www.w3.org/2001/XMLSchema#string

P407

P433

36

http://www.w3.org/2001/XMLSchema#string

P478

285

http://www.w3.org/2001/XMLSchema#string

P577

2010-06-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20592034

http://www.w3.org/2001/XMLSchema#string

P932

2934644

http://www.w3.org/2001/XMLSchema#string