Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes - Test2 - elhamkhani - TriplyDB

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

http://www.wikidata.org/entity/Q28238338

about

The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit Chemical genomics in yeast Improved microarray methods for profiling the Yeast Knockout strain collection.Detection of compound mode of action by computational integration of whole-genome measurements and genetic perturbations.Linking uracil base excision repair and 5-fluorouracil toxicity in yeast A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination Yeast and the AIDS virus: the odd couple The Mcm2-7 replicative helicase: a promising chemotherapeutic target A haploproficient interaction of the transaldolase paralogue NQM1 with the transcription factor VHR1 affects stationary phase survival and oxidative stress resistance A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis.Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae.5-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs.Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection.Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks A yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimetics Yeast toxicogenomics: genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnology Essential gene identification and drug target prioritization in Aspergillus fumigatus Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection Mitochondrial electron transport is the cellular target of the oncology drug elesclomol Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity Analysis of polymorphisms and haplotype structure of the human thymidylate synthase genetic region: a tool for pharmacogenetic studies A Ham1p-dependent mechanism and modulation of the pyrimidine biosynthetic pathway can both confer resistance to 5-fluorouracil in yeast New insights into the RNA-based mechanism of action of the anticancer drug 5'-fluorouracil in eukaryotic cells Genetic basis of haloperidol resistance in Saccharomyces cerevisiae is complex and dose dependent High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines Efforts to make and apply humanized yeast A miRNA-driven inference model to construct potential drug-disease associations for drug repositioning Large-scale prediction of drug-target relationships

P2860

Q21184023-62F6A3E2-69F9-4F35-BB90-3C385194E930 Q21245306-66257B91-557E-4772-BA2A-8091FD6F94F5 Q24556630-B1090C9D-78DD-4757-89A3-860B60A176D1 Q24563995-2E59E5E3-04E2-413D-B39A-B36DDCA455F7 Q24801410-7EFBC67A-C45F-4200-8387-164209AE038A Q24815298-EB2BEA42-FB77-4B9C-8742-C3B6A28C439E Q25255700-9F044669-2957-457E-BCC2-05B37105C8DD Q25257142-9C64F94A-F705-478F-96AE-86E89617EAEE Q26774351-F40B019A-14F5-46D5-9A7D-66F291355868 Q26776427-8F8195D4-AEC5-4711-8D24-C1149DDE1563 Q26852313-363AA168-6751-4E69-95B2-251FA80AEBA3 Q26861045-EA4C1F56-41CE-418F-933F-D204376736BF Q27930513-36E08BC1-0E5A-47EF-B45C-6B5BF5CB8262 Q27931165-3567BBBC-778B-4204-9739-D267661A78DC Q27933369-97DE3256-283A-4D86-A629-A0662039A215 Q27936292-957A9B60-BA3A-482F-86CC-14F70D60160B Q27936402-FCE48FBB-BB3B-4EB9-812F-153BC0304C12 Q27936822-AD436736-A402-4242-93F5-57B4686A860D Q27937741-EE34181F-9D9A-4EFD-8600-34D9C6270757 Q27937998-17A71070-E32F-4C11-A5E8-BFFB14BCF35D Q27938577-953DBB0D-44D2-4FD4-A43F-16D6D93C534A Q28239582-2E93AD60-3D3F-41F8-B5E4-A841E070383A Q28382899-9A85EA21-5080-4178-8469-C8EC60074D1A Q28383634-315F06B9-67E2-4BD4-96DF-D3A3DE4C87FB Q28469156-2DD42872-7F33-4F80-A971-57D5768A4A88 Q28469241-32A409FC-BCD6-4964-A2B5-C011E7B369B2 Q28473277-D04D456D-AC38-4B22-B01F-B7E0D2A28B56 Q28473456-B402C2D4-B83A-498C-BF3E-625D4E1EC3C6 Q28474096-6A5F506D-4266-4A6C-A754-B1FCB4652527 Q28475711-732311F6-D358-4741-B1A8-0160D5A8FE36 Q28478835-A8624C06-AFA2-4861-A3DB-98ED15A81081 Q28480419-A8CE5E80-CF4A-4155-8D25-44EDDA63540E Q28482151-0E6A4585-1ADE-413C-AA07-B722D0B87D82 Q28534193-E76F0F8C-BFD1-45C8-B045-06FBBF98DA92 Q28534783-D8448449-2403-4C5D-A6B2-E4399CD32C9D Q28542762-EE468E4B-7822-476B-A666-24FDFD4E9083 Q28554843-99D75DC4-E9FD-417C-A464-822236D64235 Q28602193-D5B65E0C-FDCD-44C6-9363-72F4BA195B3F Q28652746-6E4F5048-B12D-47E5-A7B9-1114B80C799D Q30002408-8D81A5E5-4D1E-4610-9EE4-4EE449373A16

P2860

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

http://www.wikidata.org/entity/Q28238338

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Discovering modes of action fo ...... screen of yeast heterozygotes

@ast

Discovering modes of action fo ...... screen of yeast heterozygotes

@en

Discovering modes of action fo ...... screen of yeast heterozygotes

@nl

type

label

Discovering modes of action fo ...... screen of yeast heterozygotes

@ast

Discovering modes of action fo ...... screen of yeast heterozygotes

@en

Discovering modes of action fo ...... screen of yeast heterozygotes

@nl

prefLabel

Discovering modes of action fo ...... screen of yeast heterozygotes

@ast

Discovering modes of action fo ...... screen of yeast heterozygotes

@en

Discovering modes of action fo ...... screen of yeast heterozygotes

@nl

P1433

Q28238338-16CF352C-4282-458A-B901-21625D56301C

P1476

Q28238338-EDACA104-3E43-4121-8286-04F14B338B41

P2093

Q28238338-04ADED2C-1312-4721-B6B6-4B063C59DDAC

Q28238338-23DF499F-80EC-466A-94E3-8EA8CC041FE8

Q28238338-2BFB9478-CB7A-4535-AA2B-1DB7F9CE6DA8

Q28238338-39581131-3EDC-4EB9-ADD9-AB466CC55D91

Q28238338-49E014FB-34F2-4AB3-8084-40D32CF66A53

Q28238338-4DE244F2-E209-4CC9-9ABD-2F3371015C6B

Q28238338-59E5F1F0-E229-4353-A094-DD8D5E2B3C0D

Q28238338-743B6331-1EB3-4CAE-9564-CDE4535BFF5C

Q28238338-8C545F53-31B5-4BFB-A1EE-8C490DA163DD

Q28238338-8F8D6C2D-29B4-4A89-9E7A-BDF9248DCE0F

P304

Q28238338-89FCD259-4781-4373-A723-008594333E72

P31

Q28238338-746C156E-BBA0-469A-A46A-401C056E3F11

P356

Q28238338-694FB2D2-9D95-4316-9487-62550C6CC349

P407

Q28238338-5B5125E5-E766-4289-BBD5-B6C459BA6254

P433

Q28238338-F6D7079F-1127-4262-8AE5-D13C7D3E250B

P478

Q28238338-5D6FD4E6-BA1B-4D6E-966B-6596472BAA5E

P577

Q28238338-E06ECBE8-D39B-48A5-ACA3-0F9250A187C3

P5875

Q28238338-B0CBFD0E-55D1-451D-A29D-2DB1E9A22BAE

P698

Q28238338-58F579A5-3503-42AF-BF64-8A8E62AB0284

P356

S0092-8674(03)01035-3

P1433

P1476

Discovering modes of action fo ...... screen of yeast heterozygotes

@en

P2093

Amy Leonardson

http://www.w3.org/2001/XMLSchema#string

Christopher D Armour

http://www.w3.org/2001/XMLSchema#string

Christopher J Roberts

http://www.w3.org/2001/XMLSchema#string

Christopher M Rush

http://www.w3.org/2001/XMLSchema#string

Daniel D Shoemaker

http://www.w3.org/2001/XMLSchema#string

Glenn D Prestwich

http://www.w3.org/2001/XMLSchema#string

Greg Schimmack

http://www.w3.org/2001/XMLSchema#string

Guy Cavet

http://www.w3.org/2001/XMLSchema#string

J Scott Butler

http://www.w3.org/2001/XMLSchema#string

Jerald C Hinshaw

http://www.w3.org/2001/XMLSchema#string

P304

121-37

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/S0092-8674(03)01035-3

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

116

http://www.w3.org/2001/XMLSchema#string

P577

2004-01-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8923403

http://www.w3.org/2001/XMLSchema#string

P698

14718172

http://www.w3.org/2001/XMLSchema#string