Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling

Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling

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http://www.wikidata.org/entity/Q28242004
Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinomaThe cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenesSelf-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex.Genetic architecture of colorectal cancer.A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destructionRegulatory single nucleotide polymorphisms (rSNPs) at the promoters 1A and 1B of the human APC geneThe two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Reconstituting regulation of the canonical Wnt pathway by engineering a minimal β-catenin destruction machine.1118-20, an indazole diarylurea compound, inhibits hepatocellular carcinoma HepG2 proliferation and tumour angiogenesis involving Wnt/β-catenin pathway and receptor tyrosine kinases.The destruction complex of beta-catenin in colorectal carcinoma and colonic adenoma.Characterization of Adenomatous Polyposis Coli Protein Dynamics and Localization at the Centrosome.Scutellaria barbata D. Don inhibits colorectal cancer growth via suppression of Wnt/β-catenin signaling pathway.Role of GSK3β in breast cancer susceptibility.Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo.Transcriptomics and machine learning predict diagnosis and severity of growth hormone deficiency.
P2860

Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling

Item
http://www.wikidata.org/entity/Q28242004
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2014 nî lūn-bûn
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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Testing models of the APC tumo ...... ction complex in Wnt signaling
@ast
Testing models of the APC tumo ...... ction complex in Wnt signaling
@en
Testing models of the APC tumo ...... ction complex in Wnt signaling
@nl
type
label
Testing models of the APC tumo ...... ction complex in Wnt signaling
@ast
Testing models of the APC tumo ...... ction complex in Wnt signaling
@en
Testing models of the APC tumo ...... ction complex in Wnt signaling
@nl
prefLabel
Testing models of the APC tumo ...... ction complex in Wnt signaling
@ast
Testing models of the APC tumo ...... ction complex in Wnt signaling
@en
Testing models of the APC tumo ...... ction complex in Wnt signaling
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
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P433
P478
P50
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P1476
Testing models of the APC tumo ...... ction complex in Wnt signaling
@en
P2093
P2860
P304
P31
P3181
P356
10.1534/GENETICS.114.166496
P407
P433
P478
P50
P577
P5875
P698
P932