Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
about
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationCarboxypeptidase E: a negative regulator of the canonical Wnt signaling pathwayThe ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingRequirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signalingHelicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and DishevelledTransmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activationIntegrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signalR-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signalingTransmembrane receptor DCC associates with protein synthesis machinery and regulates translationCaprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylationDirect inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signalingSfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signalingDisabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrinInhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor proteinDACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modificationsMolecular basis of Wnt activation via the DIX domain protein Ccd1Wnt/beta-catenin signaling and small molecule inhibitorsLGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signalingStructural basis of Wnt recognition by FrizzledWnt/beta-catenin signaling: components, mechanisms, and diseasesDishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-cateninShared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Wnt signaling: the good and the badTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapySignaling in Fibrosis: TGF-β, WNT, and YAP/TAZ ConvergeKeeping Wnt signalosome in check by vesicular trafficToggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexesThe many faces and functions of β-cateninCurrent Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible CrosstalkMitotic and mitogenic Wnt signallingMonitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells.Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration.Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingLive imaging of Xwnt5A-ROR2 complexesBili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6Crystal structures of the extracellular domain of LRP6 and its complex with DKK1Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6The Dishevelled Protein Family: Still Rather a Mystery After Over 20 Years of Molecular StudiesWnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approachesReconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6
P2860
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P2860
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@ast
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en-gb
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@nl
type
label
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@ast
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en-gb
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@nl
prefLabel
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@ast
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en-gb
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
@en
P2093
Christof Niehrs
Cristina-Maria Cruciat
Gary Davidson
Josipa Bilic
Mariann Bienz
Timo Zimmermann
Ya-Lin Huang
P2860
P304
P3181
P356
10.1126/SCIENCE.1137065
P407
P577
2007-06-15T00:00:00Z