Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors
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Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAPGTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitEnhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactomePleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factorActivation of Src family kinases by colony stimulating factor-1, and their association with its receptorControl of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variantsCsk inhibition of c-Src activity requires both the SH2 and SH3 domains of SrcThe 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1The N-terminal region of GAP regulates cytoskeletal structure and cell adhesionIn vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinasePLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migrationMEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motifPhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoThe human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5.Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changesSH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchangePhospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase CHigh-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domainsEps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signalsMolecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatmentPhosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMPA limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interactionMultiple SH2-mediated interactions in v-src-transformed cells.Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domainsMutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinaseDirect association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 betaAn Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinasesWiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domainsAssociation of the tyrosine kinase LCK with phospholipase C-gamma 1 after stimulation of the T cell antigen receptorT cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle.Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesisThe direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signalingCharacterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequencesConservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domainsInteraction domains: from simple binding events to complex cellular behavior
P2860
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P2860
Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Binding of SH2 domains of phos ...... ivated growth factor receptors
@ast
Binding of SH2 domains of phos ...... ivated growth factor receptors
@en
Binding of SH2 domains of phos ...... ivated growth factor receptors
@nl
type
label
Binding of SH2 domains of phos ...... ivated growth factor receptors
@ast
Binding of SH2 domains of phos ...... ivated growth factor receptors
@en
Binding of SH2 domains of phos ...... ivated growth factor receptors
@nl
prefLabel
Binding of SH2 domains of phos ...... ivated growth factor receptors
@ast
Binding of SH2 domains of phos ...... ivated growth factor receptors
@en
Binding of SH2 domains of phos ...... ivated growth factor receptors
@nl
P2093
P3181
P356
P1433
P1476
Binding of SH2 domains of phos ...... ivated growth factor receptors
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.2173144
P407
P577
1990-11-16T00:00:00Z