Structural basis of pore formation by the bacterial toxin pneumolysin
about
The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assemblyA novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesisHuman perforin employs different avenues to damage membranesCholesterol-dependent cytolysins, a family of versatile pore-forming toxinsRapid assembly of a multimeric membrane protein poreCholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O bindingObstructing toxin pathways by targeted pore blockageMore than a pore: the cellular response to cholesterol-dependent cytolysinsConformational changes during pore formation by the perforin-related protein pleurotolysinA new model for pore formation by cholesterol-dependent cytolysinsCryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process.A common fold mediates vertebrate defense and bacterial attackStructure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defenseCellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracisStructure of human C8 protein provides mechanistic insight into membrane pore formation by complement.Crystal Structure of Clostridium perfringens Enterotoxin Displays Features of -Pore-forming ToxinsCryo-EM structure of the ribosome–SecYE complex in the membrane environmentStructures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin RecognitionHow to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit TRAP Suggests a General MechanismStructure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen SpecificityStructural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59Defining the interaction of perforin with calcium and the phospholipid membraneCrystal structure of listeriolysin O reveals molecular details of oligomerization and pore formationSecondary structure reshuffling modulates glycosyltransferase function at the membraneStructural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent CytolysinsThe host immune dynamics of pneumococcal colonization: implications for novel vaccine developmentStructure of the poly-C9 component of the complement membrane attack complexpH dependence of listeriolysin O aggregation and pore-forming abilityCryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.Disentangling the roles of cholesterol and CD59 in intermedilysin pore formation.Revisiting the membrane interaction mechanism of a membrane-damaging β-barrel pore-forming toxin Vibrio cholerae cytolysin.Plasticity of listeriolysin O pores and its regulation by pH and unique histidine [corrected].An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin.Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysinsHemolytic lectin CEL-III heptamerizes via a large structural transition from α-helices to a β-barrel during the transmembrane pore formation process.Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel.Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.Membrane assembly of the cholesterol-dependent cytolysin pore complex.The MACPF/CDC family of pore-forming toxins.
P2860
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P2860
Structural basis of pore formation by the bacterial toxin pneumolysin
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structural basis of pore formation by the bacterial toxin pneumolysin
@ast
Structural basis of pore formation by the bacterial toxin pneumolysin
@en
Structural basis of pore formation by the bacterial toxin pneumolysin
@nl
type
label
Structural basis of pore formation by the bacterial toxin pneumolysin
@ast
Structural basis of pore formation by the bacterial toxin pneumolysin
@en
Structural basis of pore formation by the bacterial toxin pneumolysin
@nl
prefLabel
Structural basis of pore formation by the bacterial toxin pneumolysin
@ast
Structural basis of pore formation by the bacterial toxin pneumolysin
@en
Structural basis of pore formation by the bacterial toxin pneumolysin
@nl
P2093
P3181
P1433
P1476
Structural basis of pore formation by the bacterial toxin pneumolysin
@en
P2093
Helen R Saibil
Peter W Andrew
Robert J C Gilbert
Sarah J Tilley
P304
P3181
P356
10.1016/J.CELL.2005.02.033
P407
P577
2005-04-01T00:00:00Z