Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense
about
The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assemblyHuman perforin employs different avenues to damage membranesRapid assembly of a multimeric membrane protein poreCholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O bindingPutting the structure into complementElisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell DeathConformational changes during pore formation by the perforin-related protein pleurotolysinStructural basis of complement membrane attack complex formation.Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicronStructure of human C8 protein provides mechanistic insight into membrane pore formation by complement.Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59Phosphoinositide-mediated oligomerization of a defensin induces cell lysisDali server: conservation mapping in 3DCalcium-dependent permeabilization of erythrocytes by a perforin-like protein during egress of malaria parasitesKilling of Microbes and Cancer by the Immune System with Three Mammalian Pore-Forming Killer ProteinsStructure of the poly-C9 component of the complement membrane attack complexMassive expansion and functional divergence of innate immune genes in a protostomeThe Apicomplexan CDC/MACPF-like pore-forming proteins.Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysinsMonomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.Membrane assembly of the cholesterol-dependent cytolysin pore complex.Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer.The MACPF/CDC family of pore-forming toxins.Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunitStructural and functional analysis of perforin mutations in association with clinical data of familial hemophagocytic lymphohistiocytosis type 2 (FHL2) patients.Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.From protein sequences to 3D-structures and beyond: the example of the UniProt knowledgebase.Topology of the membrane-bound form of complement protein C9 probed by glycosylation mapping, anti-peptide antibody binding, and disulfide modification.Biological characterization of Chlamydia trachomatis plasticity zone MACPF domain family protein CT153.Apicomplexan perforin-like proteins.Extending the aerolysin family: from bacteria to vertebrates.Granzyme A activates another way to dieEqual force recovery in dysferlin-deficient and wild-type muscles following saponin exposure.Delivery and therapeutic potential of human granzyme B.Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within EuteleostomiEffects of MACPF/CDC proteins on lipid membranes.
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P2860
Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@ast
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@en
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@nl
type
label
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@ast
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@en
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@nl
prefLabel
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@ast
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@en
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure of C8alpha-MACPF rev ...... k in complement immune defense
@en
P2093
Dennis X Beringer
Michael A Hadders
P2860
P304
P3181
P356
10.1126/SCIENCE.1147103
P407
P577
2007-09-14T00:00:00Z