The intermediate enzymes of isoprenoid metabolism as anticancer targets
about
Prodrugs of phosphonates and phosphates: crossing the membrane barrierGeranylgeranyl diphosphate synthase: an emerging therapeutic targetProtective effect of bisphosphonates on endometrial cancer incidence in data from the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial.Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae.A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumorsUse of bisphosphonates and reduced risk of colorectal cancer.Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability.An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthasesDe novo assembly and characterization of root transcriptome in two distinct morphotypes of vetiver, Chrysopogon zizaniodes (L.) RobertyGenome wide transcriptome profiling reveals differential gene expression in secondary metabolite pathway of Cymbopogon winterianus.Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.Polyisoprenylated methylated protein methyl esterase overexpression and hyperactivity promotes lung cancer progression.Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010).Rho-kinase: regulation, (dys)function, and inhibition.Triazole-based inhibitors of geranylgeranyltransferase II.Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.Targeting geranylgeranylation reduces adrenal gland tumor burden in a murine model of prostate cancer metastasisMolecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.Regulation of polyisoprenylated methylated protein methyl esterase by polyunsaturated fatty acids and prostaglandins.Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region.Bishomoisoprenoid triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase.RNAseq analysis of hippocampal microglia after kainic acid-induced seizures.Synthesis and Biological Evaluation of a Phosphonate Phosphoantigen Prodrug
P2860
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P2860
The intermediate enzymes of isoprenoid metabolism as anticancer targets
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@ast
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@en
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@nl
type
label
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@ast
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@en
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@nl
prefLabel
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@ast
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@en
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@nl
P2093
P1476
The intermediate enzymes of isoprenoid metabolism as anticancer targets
@en
P2093
Andrew J Wiemer
David F Wiemer
Raymond J Hohl
P304
P356
10.2174/187152009788451860
P407
P577
2009-06-01T00:00:00Z