Geranylgeranyl diphosphate synthase: an emerging therapeutic target
about
Prodrugs of phosphonates and phosphates: crossing the membrane barrierP53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases3D Structure, Dimerization Modeling, and Lead Discovery by Ligand-protein Interaction Analysis of p60 Transcription Regulator Protein (p60TRP).Synthetic Routes to Methylerythritol Phosphate Pathway Intermediates and Downstream Isoprenoids.Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process.Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.Rho-kinase: regulation, (dys)function, and inhibition.Olefin Isomers of a Triazole Bisphosphonate Synergistically Inhibit Geranylgeranyl Diphosphate Synthase.A new motif for inhibitors of geranylgeranyl diphosphate synthase.In vitro studies in a myelogenous leukemia cell line suggest an organized binding of geranylgeranyl diphosphate synthase inhibitorsThe interplay between cell signalling and the mevalonate pathway in cancer.Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase.Triazole-based inhibitors of geranylgeranyltransferase II.Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.Stereoselective Synthesis of Homoneryl and Homogeranyl Triazole Bisphosphonates.Synthesis of isoprenoid bisphosphonate ethers through C-P bond formations: Potential inhibitors of geranylgeranyl diphosphate synthase.Potent Triazole Bisphosphonate Inhibitor of Geranylgeranyl Diphosphate Synthase.
P2860
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P2860
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@ast
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@en
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@nl
type
label
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@ast
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@en
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@nl
prefLabel
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@ast
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@en
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@nl
P2093
P2860
P3181
P356
P1476
Geranylgeranyl diphosphate synthase: an emerging therapeutic target
@en
P2093
P2860
P304
P3181
P356
10.1038/CLPT.2011.215
P407
P577
2011-12-01T00:00:00Z