Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations
about
Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activityStructural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complexSubunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complexCryptic proteolytic activity of dihydrolipoamide dehydrogenaseTriazaspirodimethoxybenzoyls as Selective Inhibitors of Mycobacterial Lipoamide Dehydrogenase,Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: Implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanismStructural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain -Ketoacid Dehydrogenase ComplexInsight to the Interaction of the Dihydrolipoamide Acetyltransferase (E2) Core with the Peripheral Components in the Escherichia coli Pyruvate Dehydrogenase Complex via Multifaceted Structural ApproachesIrc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiaeMitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complexCrystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosisHeart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathyChanges in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brainStructural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry: Implications for the structural basis of E3 deficiency.The pyruvate dehydrogenase complexes: structure-based function and regulation.A core metabolic enzyme mediates resistance to phosphine gas.TAT opens the door.Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate.A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms.Determination of protein complex stoichiometry through multisignal sedimentation velocity experiments.Elucidation of the interaction loci of the human pyruvate dehydrogenase complex E2·E3BP core with pyruvate dehydrogenase kinase 1 and kinase 2 by H/D exchange mass spectrometry and nuclear magnetic resonanceCardiomyopathy of Friedreich's ataxia: use of mouse models to understand human disease and guide therapeutic development.ATP synthase subunit alpha and LV mass in ischaemic human hearts.Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells.Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.Reversible inactivation of dihydrolipoamide dehydrogenase by Angeli's salt.Global Kinetic Analysis of Mammalian E3 Reveals pH-dependent NAD+/NADH Regulation, Physiological Kinetic Reversibility, and Catalytic OptimumPhosphine resistance in India is characterised by a dihydrolipoamide dehydrogenase variant that is otherwise unobserved in eukaryotes.Genetic Conservation of Phosphine Resistance in the Rice Weevil Sitophilus oryzae (L.).Proteins with neomorphic moonlighting functions in disease.Nuclear magnetic resonance approaches in the study of 2-oxo acid dehydrogenase multienzyme complexes--a literature review.A new level of architectural complexity in the human pyruvate dehydrogenase complex.Dihydrolipoamide dehydrogenase mutation alters the NADH sensitivity of pyruvate dehydrogenase complex of Escherichia coli K-12.DNA microarray analysis of genes differentially expressed in adipocyte differentiation.Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment.Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex.Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components.Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide.
P2860
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P2860
Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Crystal structure of human dih ...... s of disease-causing mutations
@ast
Crystal structure of human dih ...... s of disease-causing mutations
@en
Crystal structure of human dih ...... s of disease-causing mutations
@nl
type
label
Crystal structure of human dih ...... s of disease-causing mutations
@ast
Crystal structure of human dih ...... s of disease-causing mutations
@en
Crystal structure of human dih ...... s of disease-causing mutations
@nl
prefLabel
Crystal structure of human dih ...... s of disease-causing mutations
@ast
Crystal structure of human dih ...... s of disease-causing mutations
@en
Crystal structure of human dih ...... s of disease-causing mutations
@nl
P50
P1476
Crystal structure of human dih ...... s of disease-causing mutations
@en
P2093
David T Chuang
Jacinta L Chuang
P304
P356
10.1016/J.JMB.2005.05.014
P407
P577
2005-07-15T00:00:00Z