Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation
about
The HTLV-1 Tax interactomeTORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeatsHuman T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 proteinRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityProgress, challenges, and responsibilities in retrovirologyRetrovirology highlights a quarter century of HTLV-I researchTwo discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cellsHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cellsPresence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein.HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZPreclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseasesCREB--a real culprit in oncogenesisTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Complex cell cycle abnormalities caused by human T-lymphotropic virus type 1 Tax.Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit.Regulation of human T-lymphotropic virus type I latency and reactivation by HBZ and Rex.Hematopoietic stem cells and retroviral infection.Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule.HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1)Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo.An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoproteinHTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cellsVisualizing spatiotemporal dynamics of apoptosis after G1 arrest by human T cell leukemia virus type 1 Tax and insights into gene expression changes using microarray-based gene expression analysis.Natural history of adult T-cell leukemia/lymphoma and approaches to therapy.HTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death.The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication.Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemiaActivation of the anaphase promoting complex by HTLV-1 tax leads to senescence.Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription.BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSPEffect of phosphonated carbocyclic 2'-oxa-3'-aza-nucleoside on human T-cell leukemia virus type 1 infection in vitro.Viral carcinogenesis: factors inducing DNA damage and virus integrationPeripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheepHuman T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma
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P2860
Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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Life, death, and tax: role of ...... ty and cellular transformation
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P2093
P2860
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Life, death, and tax: role of ...... ty and cellular transformation
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P2093
Chou-zen Giam
Franca Majone
Mordechai Aboud
P2860
P304
P3181
P356
10.1074/JBC.R400009200
P407
P577
2004-07-30T00:00:00Z