Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
about
The HTLV-1 Tax interactomeHighlights on distinctive structural and functional properties of HTLV Tax proteinsBub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisHost-pathogen interactome mapping for HTLV-1 and -2 retrovirusesA human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomesCharacterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCEvidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2betaHepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformationZyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressorGAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytesp55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinaseMAD2B is an inhibitor of the anaphase-promoting complexImpairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomasCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointCrystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1Identification of two novel components of the human NDC80 kinetochore complexSimian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signalingIdentification of a MAD2-binding protein, CMT2, and its role in mitosis.Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Lesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiaeCheckpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complexTORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeatsIdentification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulationThe checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiationViruses associated with human cancerCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregationSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityMad2 transiently associates with an APC/p55Cdc complex during mitosisSpindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochoresHuman MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochoresRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityHuman T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanismsA balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytesHTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZ
P2860
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P2860
Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@ast
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en-gb
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@nl
type
label
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@ast
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en-gb
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@nl
prefLabel
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@ast
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en-gb
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@nl
P2093
P921
P3181
P1433
P1476
Human T cell leukemia virus ty ...... itotic checkpoint protein MAD1
@en
P2093
P3181
P356
10.1016/S0092-8674(00)81148-4
P407
P577
1998-04-03T00:00:00Z