Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
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Rac and Rho GTPases in cancer cell motility controlSemaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPaseSemaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeletonDeaf-1 regulates epithelial cell proliferation and side-branching in the mammary glandThe Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migrationRAC3 is a pro-migratory co-activator of ERαELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomasApproaches of targeting Rho GTPases in cancer drug discoveryRegulation of Macrophage Polarization by RON Receptor Tyrosine Kinase SignalingInference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of CancerInhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division.RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells.Dual role of Cdc42 in spindle orientation control of adherent cellsRole of Rac1-dependent NADPH oxidase in the growth of pancreatic cancer.Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagenThe Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration.The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migrationTherapeutic strategies for inhibiting invasion in glioblastoma.Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo.Myt3 Mediates Laminin-V/Integrin-β1-Induced Islet-Cell Migration via TgfbiLoss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signalingThe tumor suppressor role of miR-124 in osteosarcomaInduction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cellsThe Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell linesAberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation.TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling.Expression of Rac-1 related to tumor depth, lymph node metastasis and patient prognosis in esophageal squamous cell carcinoma.Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry.Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cellsRac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis.An integer linear programming approach for finding deregulated subgraphs in regulatory networks.Characterization of EHop-016, novel small molecule inhibitor of Rac GTPaseA critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells
P2860
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P2860
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@ast
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@en
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@nl
type
label
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@ast
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@en
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@nl
prefLabel
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@ast
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@en
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@nl
P2093
P2860
P356
P1433
P1476
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
@en
P2093
David Michaelson
Marc Symons
Mark R Philips
Salvatore J Coniglio
Ya-yu Chuang
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208909
P407
P577
2005-11-01T00:00:00Z
P5875
P6179
1031154672