1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists
about
Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine classMultiple receptors contribute to the behavioral effects of indoleamine hallucinogens.'Hybrid' benzofuran-benzopyran congeners as rigid analogs of hallucinogenic phenethylaminesAgonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivoThe role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligandsRecent advances in the neuropsychopharmacology of serotonergic hallucinogensStructure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptorsDual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists.Animal models of serotonergic psychedelics.Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT)Intracranial self-stimulation to evaluate abuse potential of drugs.Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network4-Bromo-2,5-dimethoxyphenethylamine (2C-B): presence in the recreational drug market in Spain, pattern of use and subjective effects.Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists.Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT₂A receptors, in mice.The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens.Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male ratsRole for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures.Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.Endocannabinoids blunt the augmentation of synaptic transmission by serotonin 2A receptors in the nucleus tractus solitarii (nTS).Role of the 5-HT₂A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice.Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function.Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization.Effect of a hallucinogenic serotonin 5-HT2A receptor agonist on visually guided, hippocampal-dependent spatial cognition in C57BL/6J mice.Chemistry and Structure-Activity Relationships of Psychedelics.A systematic investigation of the differential roles for ventral tegmentum serotonin 1- and 2-type receptors on food intake in the rat.Activation of 5-HT2A receptor disrupts rat maternal behavior.Organocatalytic silyl transfer from silylborane to nitroalkenes for the synthesis of β-silyl nitroalkanes and β-silyl amines.
P2860
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P2860
1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@ast
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@en
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@nl
type
label
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@ast
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@en
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@nl
prefLabel
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@ast
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@en
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@nl
P2093
P3181
P356
P1476
1-Aminomethylbenzocycloalkanes ...... ctive 5-HT2A receptor agonists
@en
P2093
Alejandra Gallardo-Godoy
Danuta Marona-Lewicka
David E Nichols
Jason C Parrish
Michael R Braden
Thomas H McLean
P304
P3181
P356
10.1021/JM060656O
P407
P577
2006-09-21T00:00:00Z