Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system
about
BAG-1 modulates the chaperone activity of Hsp70/Hsc70.Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptorHeat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1Genetic analysis of viable Hsp90 alleles reveals a critical role in Drosophila spermatogenesisp50(cdc37) acting in concert with Hsp90 is required for Raf-1 functionThe human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refoldingPhosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: regulation of HSP90-binding activity of FKBP52CDC37 is required for p60v-src activity in yeastReview: The HSP90 molecular chaperone-an enigmatic ATPaseTargeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsFunctions of the Hsp90 chaperone system: lifting client proteins to new heightsCns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40-dependent functions in cpr7Delta cellsMutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase.In vivo analysis of the Hsp90 cochaperone Sti1 (p60)Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperonesMEK kinase activity is not necessary for Raf-1 function.Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathwayIdentification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK bindingRas-induced activation of Raf-1 is dependent on tyrosine phosphorylationRegulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro.Raf-1 N-terminal sequences necessary for Ras-Raf interaction and signal transduction.Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts.The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in DrosophilaATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo.The oncoprotein kinase chaperone CDC37 functions as an oncogene in mice and collaborates with both c-myc and cyclin D1 in transformation of multiple tissuesMutations Modulating Raf signaling in Drosophila eye development.Characterization of maternal and zygotic D-raf proteins: dominant negative effects on Torso signal transduction.A mutation in an HSP90 gene affects the sexual cycle and suppresses vegetative incompatibility in the fungus Podospora anserina.A role for Hsp90 in retinoid receptor signal transductionStructure of an Hsp90-Cdc37-Cdk4 complex.Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinicThree-dimensional culture regulates Raf-1 expression to modulate fibronectin matrix assemblyA model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesIntegrated genomics and proteomics of the Torpedo californica electric organ: concordance with the mammalian neuromuscular junctionModulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitinationHSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells.Role of phosphorylation sites and the C2 domain in regulation of cytosolic phospholipase A2.The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors.
P2860
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P2860
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Raf exists in a native heteroc ...... stituted in a cell-free system
@ast
Raf exists in a native heteroc ...... stituted in a cell-free system
@en
Raf exists in a native heteroc ...... stituted in a cell-free system
@nl
type
label
Raf exists in a native heteroc ...... stituted in a cell-free system
@ast
Raf exists in a native heteroc ...... stituted in a cell-free system
@en
Raf exists in a native heteroc ...... stituted in a cell-free system
@nl
prefLabel
Raf exists in a native heteroc ...... stituted in a cell-free system
@ast
Raf exists in a native heteroc ...... stituted in a cell-free system
@en
Raf exists in a native heteroc ...... stituted in a cell-free system
@nl
P2093
P1476
Raf exists in a native heteroc ...... stituted in a cell-free system
@en
P2093
P304
21711-21716
P407
P577
1993-10-01T00:00:00Z