Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
about
Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenalStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseManipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicityRegulation of glutathione synthesisSignificance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid TumorsOxidative stress responses and NRF2 in human leukaemiaGlutathione: new roles in redox signaling for an old antioxidantDietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC InhibitionSchisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathwayGlutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian FailureEffect of chronic glutathione deficiency on the behavioral phenotype of Gclm-/- knockout mice.Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative StressRapid activation of glutamate cysteine ligase following oxidative stress.Oxidative Stress Genes, Antioxidants and Coronary Artery Disease in Type 2 Diabetes Mellitus.Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells.Mechanisms of gamma-glutamylcysteine ligase regulationA systems biology perspective on Nrf2-mediated antioxidant responseAstrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibitionGSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.Antioxidant defenses in the ocular surface.Age-related transcriptional changes in gene expression in different organs of mice support the metabolic stability theory of aging.Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.Circadian regulation of glutathione levels and biosynthesis in Drosophila melanogaster.Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice.Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility geneFocus on molecular events in the anterior chamber leading to glaucoma.Transgenic mouse models for alcohol metabolism, toxicity, and cancer.Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunitsAging alters circadian regulation of redox in Drosophila.Comparative proteomic analysis of the molecular responses of mouse macrophages to titanium dioxide and copper oxide nanoparticles unravels some toxic mechanisms for copper oxide nanoparticles in macrophages.Lipid metabolism and body composition in Gclm(-/-) mice.The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice.Emerging regulatory paradigms in glutathione metabolism.Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake.Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cellsGain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice.Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis modelHepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice.Nuclear localization of glutamate-cysteine ligase is associated with proliferation in head and neck squamous cell carcinoma
P2860
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P2860
Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@ast
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@en
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@nl
type
label
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@ast
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@en
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@nl
prefLabel
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@ast
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@en
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@nl
P2093
P2860
P3181
P356
P1476
Glutamate cysteine ligase cata ...... n of tissue glutathione levels
@en
P2093
Daniel W Nebert
Howard G Shertzer
Scott N Schneider
Timothy P Dalton
P2860
P304
P3181
P356
10.1074/JBC.M504604200
P407
P577
2005-10-07T00:00:00Z