The concept of synthetic lethality in the context of anticancer therapy
about
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivoIn-silico human genomics with GeneCardsTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesCancer vulnerabilities unveiled by genomic lossThe splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesionStructures of YAP protein domains reveal promising targets for development of new cancer drugsFailure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitroHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesCancer cells and normal cells differ in their requirements for Thoc1Radioresistance of Brain TumorsTargeting Oncogenic Mutant p53 for Cancer TherapyBridging academic science and clinical research in the search for novel targeted anti-cancer agentsNext-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us?Effectiveness and safety of poly (ADP-ribose) polymerase inhibitors in cancer therapy: A systematic review and meta-analysisUsing large-scale genomics data to identify driver mutations in lung cancer: methods and challengesProtecting the normal in order to better kill the cancerTargeting melanoma by small molecules: challenges aheadDiversity-oriented synthetic strategies applied to cancer chemical biology and drug discoveryPersonalised cancer medicineNext-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneityGenomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancersWill kinase inhibitors make it as glioblastoma drugs?Small-molecule inhibitors of the Myc oncoproteinNovel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive reviewThe human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopyFine tuning chemotherapy to match BRCA1 statusCancer's Achilles' Heel: Apoptosis and Necroptosis to the RescueUse of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinicPredictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized MedicineSynthetic lethality in lung cancer and translation to clinical therapiesUpdate on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatmentDrugging the addict: non-oncogene addiction as a target for cancer therapyPrediction of Genetic Interactions Using Machine Learning and Network PropertiesTargeted cancer therapies based on the inhibition of DNA strand break repairRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancersSurvivin: potential role in diagnosis, prognosis and targeted therapy of gastric cancerNovel insights into the molecular origins and treatment of lung cancerPre-clinical drug prioritization via prognosis-guided genetic interaction networks
P2860
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P2860
The concept of synthetic lethality in the context of anticancer therapy
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The concept of synthetic lethality in the context of anticancer therapy
@ast
The concept of synthetic lethality in the context of anticancer therapy
@en
The concept of synthetic lethality in the context of anticancer therapy
@nl
type
label
The concept of synthetic lethality in the context of anticancer therapy
@ast
The concept of synthetic lethality in the context of anticancer therapy
@en
The concept of synthetic lethality in the context of anticancer therapy
@nl
prefLabel
The concept of synthetic lethality in the context of anticancer therapy
@ast
The concept of synthetic lethality in the context of anticancer therapy
@en
The concept of synthetic lethality in the context of anticancer therapy
@nl
P2860
P3181
P356
P1476
The concept of synthetic lethality in the context of anticancer therapy
@en
P2860
P2888
P304
P3181
P356
10.1038/NRC1691
P407
P577
2005-09-01T00:00:00Z
P5875
P6179
1052792626