The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge - Test2 - elhamkhani - TriplyDB

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

http://www.wikidata.org/entity/Q28268615

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Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma Scrib regulates PAK activity during the cell migration process Epidermal wound repair is regulated by the planar cell polarity signaling pathway Cell polarity signaling in the plasticity of cancer cell invasiveness Rho GTPases in collective cell migration A Cilia Independent Role of Ift88/Polaris during Cell Migration Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland The Mammalian Blood-Testis Barrier: Its Biology and Regulation Aberrant overexpression of the cell polarity module scribble in human cancer The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis Discovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein Scribble 3D Cultures of prostate cancer cells cultured in a novel high-throughput culture platform are more resistant to chemotherapeutics compared to cells cultured in monolayer Scribble interacts with beta-catenin to localize synaptic vesicles to synapses Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells.The LKB1-AMPK pathway: metabolism and growth control in tumour suppression Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2.Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.Real-time monitoring of cell protrusion dynamics by impedance responses.Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Scribble at the crossroads.Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.Tissue polarity-dependent control of mammary epithelial homeostasis and cancer development: an epigenetic perspective.Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers Establishment of epithelial polarity--GEF who's minding the GAP?The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Role of the polarity protein Scribble for podocyte differentiation and maintenance Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes Protein complexes that control renal epithelial polarity.Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.Spectrin binding motifs regulate Scribble cortical dynamics and polarity function.Expression of polarity genes in human cancer.SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells.

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P2860

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

http://www.wikidata.org/entity/Q28268615

description

2007 nî lūn-bûn

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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2007 թվականի ապրիլին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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The tumour-suppressor Scribble ...... ecruitment to the leading edge

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The tumour-suppressor Scribble ...... ecruitment to the leading edge

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A S Peterson

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J Caddy

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J S Kauffman

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K Zarbalis

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L E Dow

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P2860

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

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10.1038/SJ.ONC.1210016

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16

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26

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