The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge
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Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinomaScrib regulates PAK activity during the cell migration processEpidermal wound repair is regulated by the planar cell polarity signaling pathwayCell polarity signaling in the plasticity of cancer cell invasivenessRho GTPases in collective cell migrationA Cilia Independent Role of Ift88/Polaris during Cell MigrationScribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandThe Mammalian Blood-Testis Barrier: Its Biology and RegulationAberrant overexpression of the cell polarity module scribble in human cancerThe PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesisDiscovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein Scribble3D Cultures of prostate cancer cells cultured in a novel high-throughput culture platform are more resistant to chemotherapeutics compared to cells cultured in monolayerScribble interacts with beta-catenin to localize synaptic vesicles to synapsesSyntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells.The LKB1-AMPK pathway: metabolism and growth control in tumour suppressionNon-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2.Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.Real-time monitoring of cell protrusion dynamics by impedance responses.Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Scribble at the crossroads.Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.Tissue polarity-dependent control of mammary epithelial homeostasis and cancer development: an epigenetic perspective.Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancerPolarity protein complex Scribble/Lgl/Dlg and epithelial cell barriersEstablishment of epithelial polarity--GEF who's minding the GAP?The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Role of the polarity protein Scribble for podocyte differentiation and maintenanceAbnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytesProtein complexes that control renal epithelial polarity.Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development.Spectrin binding motifs regulate Scribble cortical dynamics and polarity function.Expression of polarity genes in human cancer.SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasiamiR-296 regulation of a cell polarity-cell plasticity module controls tumor progression.High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells.
P2860
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P2860
The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@ast
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@en
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@nl
type
label
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@ast
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@en
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@nl
prefLabel
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@ast
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@en
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@nl
P2093
P2860
P356
P1433
P1476
The tumour-suppressor Scribble ...... ecruitment to the leading edge
@en
P2093
A S Peterson
J S Kauffman
K Zarbalis
P O Humbert
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210016
P407
P577
2007-04-05T00:00:00Z
P5875
P6179
1022907317