UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
about
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary originIRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansToll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2The structural biology of Toll-like receptorsRecognition of lipopolysaccharide pattern by TLR4 complexesA novel Toll-like receptor that recognizes vesicular stomatitis virusUNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondiiPathogen recognition and inflammatory signaling in innate immune defensesMicrobe sensing, positive feedback loops, and the pathogenesis of inflammatory diseasesCross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsIdentifying novel spatiotemporal regulators of innate immunityTyrosine phosphorylation in Toll-like receptor signalingHost innate immune responses to sepsisPhagosomal TLR signaling upon Borrelia burgdorferi infectionRNA mediated Toll-like receptor stimulation in health and diseaseThe effects of TLR activation on T-cell development and differentiationNucleic acids and endosomal pattern recognition: how to tell friend from foe?TLR8: the forgotten relative revindicatedUNC93B1 mediates host resistance to infection with Toxoplasma gondiiThe Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicingAsparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activationMutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivoThe role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsThe Role of Toll-Like Receptors in Hematopoietic MalignanciesSexual dimorphism in autoimmunityCytoplasmic DNA innate immune pathwaysInnate immune pattern recognition: a cell biological perspectiveHaploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligasesGuanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cellsCD14 controls the LPS-induced endocytosis of Toll-like receptor 4Systems biology of innate immunityPIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signalingThe ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.Pathogen recognition by the innate immune systemMammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking.The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response.
P2860
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P2860
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@ast
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@en
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@nl
type
label
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@ast
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@en
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@nl
prefLabel
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@ast
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@en
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@nl
P921
P3181
P356
P1433
P1476
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
@en
P2093
Hidde L Ploegh
Marie-Eve Paquet
P2888
P304
P3181
P356
10.1038/NATURE06726
P407
P577
2008-02-27T00:00:00Z
P6179
1000502553