Integrins regulate the association and phosphorylation of paxillin by c-Abl
about
Integrin and GPCR Crosstalk in the Regulation of ASM Contraction Signaling in AsthmaScar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffoldc-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1Abl kinase interacts with and phosphorylates vinexinRNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localizationBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinPaxillin comes of ageNRP1 function and targeting in neurovascular development and eye diseaseGleevec, an Abl family inhibitor, produces a profound change in cell shape and migrationDok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganizationMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorInhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexesPhosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesisModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionTarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1c-Abl Kinase Is a Regulator of αvβ3 Integrin Mediated Melanoma A375 Cell Migration.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.Paxillin: a focal adhesion-associated adaptor protein.Inhibition of c-Abl tyrosine kinase activity by filamentous actin.Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells.Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization.Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cellsGenetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells.Effector caspases and leukemiaDirect interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injuryTargeting Abl kinases to regulate vascular leak during sepsis and acute respiratory distress syndrome.The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesionActivation of abl family kinases in solid tumors.The Lhx9-integrin pathway is essential for positioning of the proepicardial organ.Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domainsPaxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.
P2860
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P2860
Integrins regulate the association and phosphorylation of paxillin by c-Abl
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@ast
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@en
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@nl
type
label
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@ast
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@en
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@nl
prefLabel
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@ast
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@en
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@nl
P2860
P3181
P356
P1476
Integrins regulate the association and phosphorylation of paxillin by c-Abl
@en
P2093
P2860
P304
14225-14230
P3181
P356
10.1074/JBC.273.23.14225
P407
P577
1998-06-01T00:00:00Z