Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
about
Abl kinase interacts with and phosphorylates vinexinABL tyrosine kinases: evolution of function, regulation, and specificityCdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsDok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganizationUnc119 protects from Shigella infection by inhibiting the Abl family kinasesThe Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actinc-Abl phosphorylates Dok1 to promote filopodia during cell spreadingModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionAbelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.Using Bcr-Abl to examine mechanisms by which abl kinase regulates morphogenesis in Drosophila.Caspase-dependent cleavage of c-Abl contributes to apoptosis.In the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS.Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors.c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.Activated Fes protein tyrosine kinase induces terminal macrophage differentiation of myeloid progenitors (U937 cells) and activation of the transcription factor PU.1.c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton.Actin polymerization negatively regulates p53 function by impairing its nuclear import in response to DNA damage.The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus.Role of zinc metallothionein-3 (ZnMt3) in epidermal growth factor (EGF)-induced c-Abl protein activation and actin polymerization in cultured astrocytes.Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cellControlling Abl: auto-inhibition and co-inhibition?The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cellsNucleo-cytoplasmic communication in apoptotic response to genotoxic and inflammatory stress.Self-feedback in actin polymerizationActivation of abl family kinases in solid tumors.Distinct functional domains of the Abelson tyrosine kinase control axon guidance responses to Netrin and Slit to regulate the assembly of neural circuits.Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals.N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor.c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expressionThe capable ABL: what is its biological function?A multi-parameter in vitro screen in human stem cell-derived cardiomyocytes identifies ponatinib-induced structural and functional cardiac toxicity.
P2860
Q24296684-CD54E77F-C1C4-477E-ACE8-1DAD53D76844Q24299738-823B1562-9D10-479B-B5F2-D5DE302F4C74Q24314378-439F672A-8649-49F7-9BA4-1C7FA64E4D44Q24652254-CF6A01CD-EC39-4875-AFB2-F3D15587459BQ28207727-C9F54CA4-B6F9-4CD8-9BA1-E89C300FA14AQ28475302-3563D052-97E5-4A77-967D-134A0C5B4207Q28508973-FBC4154E-8B96-467E-9F69-C1AB4E4FAC32Q28510526-52BD8AD6-CA72-4810-8F36-4865176CDCE4Q28591494-6034D574-F4D0-4AF8-9239-F4E528C00C7EQ30008895-B1E6CEC6-2B42-4E62-B986-3E22ACBD605FQ30010077-26C071D6-86FF-4453-B614-572F121616BFQ30157529-B994B903-0903-41E6-9FF2-4B11C7BF179CQ30160360-CF8C4E2A-56BB-42C5-9CEB-FB051DA9EFFDQ30374671-CFB8A978-51B9-4324-84DD-B3EC7D82B80CQ30444235-84355717-C631-4769-A98D-9601E2A36D44Q30450695-1B0AB718-0274-439A-B3C3-D4EF405D4004Q30480984-16708396-08AB-44F6-B71C-F700BAC8CAD0Q33186569-93DB2579-4BD5-478A-89BB-4AF05428CE8CQ33547449-24743DD2-96F7-4911-8CEB-2F868DF2B02EQ33613286-F4AB5D4E-EEB1-4848-BCBE-E17E4F99654DQ33780290-A00040ED-022C-4A9D-AEFD-DA1DA4914AFFQ33828334-8DEDDE9A-7C6B-423C-8C7B-8B50317772FBQ34323999-F60E165E-2CCD-400E-9530-225388EB47E2Q34374088-3994588B-8755-4C33-AACB-1325E360AE8FQ34403933-D9504826-D6D9-4C0B-949B-2F7CCB6361CFQ34658173-AB5912A3-E432-4978-9F95-87FCB6A3E0FAQ34859191-ED2F76D5-260C-490E-BA0A-D222FB12D3BEQ35562577-F60AB81F-CC91-41C0-83D9-21831D99A6D1Q35606814-97B4E02D-310E-4B6E-BCA3-A785EAD445E4Q35620042-1ADEF192-DA2A-4CE3-9C7E-73D11ABA4A20Q35633302-F3ADFB7D-B723-4169-BEB6-524939F18D91Q36027368-EBDCF72D-CDCB-458E-87E5-8F7730085BFCQ36100514-2447FD33-01B0-4200-BD72-B82456B93D73Q36443421-3B6932FA-60AE-46BE-9E88-3BFF76F87C07Q36918092-68005D5E-62D7-4C8D-8B7D-F47D2033B896Q37031466-4A3E932A-5905-4EC5-8B7F-D258BAD79A0AQ37431212-99F4C603-D313-4864-94BA-4FF495F49DD4Q37684429-F1A411E2-018B-475D-A4AD-3532B2CF822AQ37713585-B13FF0C9-266E-4AC7-B885-7A22C43D9BAEQ38949052-D47A4D23-170F-43B3-B858-CFAD5C44D040
P2860
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@ast
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@en
type
label
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@ast
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@en
prefLabel
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@ast
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@en
P2093
P2860
P356
P1476
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
@en
P2093
P2860
P304
27104-27110
P356
10.1074/JBC.M100559200
P407
P577
2001-04-17T00:00:00Z