Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis - Test2 - elhamkhani - TriplyDB

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

http://www.wikidata.org/entity/Q28274000

about

Tensor GSVD of patient- and platform-matched tumor and normal DNA copy-number profiles uncovers chromosome arm-wide patterns of tumor-exclusive platform-consistent alterations encoding for cell transformation and predicting ovarian cancer survival Phosphorylation: the molecular switch of double-strand break repair CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repair Inhibition of homologous recombination by the PCNA-interacting protein PARI Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51 The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems Newer gene editing technologies toward HIV gene therapy MicroRNA-182-5p targets a network of genes involved in DNA repair Epigenetics and aging How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway DNA repair and aging: the impact of the p53 family Inhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer Therapy Pluripotent stem cells and gene therapy DNA damage response and prostate cancer: defects, regulation and therapeutic implications DNA DSB repair pathway choice: an orchestrated handover mechanism DNA double-strand break repair pathway choice and cancer New approaches to radiation protection DNA Damage and Pulmonary Hypertension Autophagy-mediated tumor promotion Repair of strand breaks by homologous recombination DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclin D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1 The DNA Damage Response: Making It Safe to Play with Knives Genome editing: the road of CRISPR/Cas9 from bench to clinic DNA Polymerase θ: A Unique Multifunctional End-Joining Machine Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome Gene therapy for hemophilia Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins Therapeutic genome editing: prospects and challenges A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

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P2860

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

http://www.wikidata.org/entity/Q28274000

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@ast

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@en

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@nl

type

label

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@ast

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@en

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@nl

prefLabel

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@ast

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@en

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@nl

P1433

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P1433

Nature Reviews Molecular Cell Biology

P1476

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

@en

P2860

DNA Damage, Aging, and Cancer

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

The BRCT domain is a phospho-protein binding domain

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

P2888

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196-207

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scholarly article

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224469

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10.1038/NRM2851

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3

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11

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Mary Ellen Moynahan

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2010-03-01T00:00:00Z

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41532664

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1051814387

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20177395

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3261768

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