A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination
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Replication-Associated Recombinational Repair: Lessons from Budding YeastInterplay between Fanconi anemia and homologous recombination pathways in genome integrityDNA repair targeted therapy: The past or future of cancer treatment?Update of the human and mouse Fanconi anemia genesHigh-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsThe Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination PhenotypeDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMThe genomics of inherited bone marrow failure: from mechanism to the clinic.Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium InternatiCongenital Mirror Movements Due to RAD51: Cosegregation with a Nonsense Mutation in a Norwegian Pedigree and Review of the LiteratureCryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour DevelopmentA Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to ChemotherapyNEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protectionRadiation Sensitivity and Radiation Necrosis in the Short Telomere SyndromesFan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.Paternal or Maternal Uniparental Disomy of Chromosome 16 Resulting in Homozygosity of a Mutant Allele Causes Fanconi AnemiaFANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks.Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans.The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia.Novel insights into RAD51 activity and regulation during homologous recombination and DNA replicationBRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.What is the DNA repair defect underlying Fanconi anemia?The homologous recombination protein RAD51 is a promising therapeutic target for cervical carcinomaDigital gene expression profiling analysis of DNA repair pathways in colon cancer stem population of HT29 cells.FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway.Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia.Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damageDisruption of SLX4-MUS81 Function Increases the Relative Biological Effectiveness of Proton Radiationp53 downregulates the Fanconi anaemia DNA repair pathway.A strategy for molecular diagnostics of Fanconi anemia in Brazilian patients.Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.Efficient CRISPR/Cas9-Mediated Genome Editing Using a Chimeric Single-Guide RNA Molecule.
P2860
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P2860
A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination
description
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
@ast
im August 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2015/08/06)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/08/06)
@nl
наукова стаття, опублікована в серпні 2015
@uk
مقالة علمية (نشرت في 6-8-2015)
@ar
name
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@ast
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@en
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@nl
type
label
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@ast
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@en
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@nl
prefLabel
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@ast
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@en
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@nl
P2093
P2860
P50
P3181
P1433
P1476
A Dominant Mutation in Human R ...... nt of Homologous Recombination
@en
P2093
Athena L Huang
Avinash Abhyankar
Belinda K Cornes
Brooke A Conti
Carrie Sougnez
Erica M Sanborn
Francis P Lach
Henrik Molina
John E Wagner
Stacey B Gabriel
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2015.07.009
P577
2015-08-06T00:00:00Z