Disruption of GW bodies impairs mammalian RNA interference - Test2 - elhamkhani - TriplyDB

Disruption of GW bodies impairs mammalian RNA interference

Disruption of GW bodies impairs mammalian RNA interference

http://www.wikidata.org/entity/Q28281500

about

Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54 Identification of novel homologous microRNA genes in the rhesus macaque genome Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2 Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system Structural features of Argonaute-GW182 protein interactions mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes Kinetic signatures of microRNA modes of action Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells Deadenylation is a widespread effect of miRNA regulation Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.RNA granules An Emerging Role of micro-RNA in the Effect of the Endocrine Disruptors RNA-binding proteins related to stress response and differentiation in protozoa RNA Interference for Functional Genomics and Improvement of Cotton (Gossypium sp.)Regulation of mammalian transcription and splicing by Nuclear RNAi Mechanisms of deadenylation-dependent decay Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing Origins and Mechanisms of miRNAs and siRNAs Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae.A role for Q/N-rich aggregation-prone regions in P-body localization.Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae.P bodies promote stress granule assembly in Saccharomyces cerevisiae.Achieving HIV-1 Control through RNA-Directed Gene Regulation TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2 CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm DISC1-dependent switch from progenitor proliferation to migration in the developing cortex Monocyte chemotactic protein-induced protein 1 (MCPIP1) suppresses stress granule formation and determines apoptosis under stress MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation Nuclear outsourcing of RNA interference components to human mitochondria Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

P2860

Q21090536-DC788601-D308-4191-BBE4-DA99909A767D Q21146051-F1E10116-3892-458D-9906-45CC2BDC7BD9 Q21263152-71057F1D-FFA1-427D-9B4C-FB3C8EE5179F Q24301405-D81D6204-1060-4A6D-A707-F21ADE4D9B5A Q24305036-5A01611C-78A5-40BA-BE3C-13BD7A071A89 Q24310166-23601374-5788-43A2-9D30-99B07A68EBFE Q24314993-3AED79B8-2784-4E93-9AF3-C4CDE1D305C1 Q24318187-096AB646-83F7-4A80-AE07-F3CFF6FA3EEA Q24321947-9785936F-4344-4965-B19E-325DF426F86C Q24328771-2C133C10-9956-4CC9-A043-70C3933C4FBA Q24336642-A57D44BD-6340-44CD-91BE-97B4F9CB3D10 Q24554481-D486F127-1B1C-4D78-BA00-576AE4C2D86B Q24613847-63562C03-BBB7-4F68-9A22-8E30C87DC9CF Q24632574-6298765B-D5D1-4819-A07A-A42BE937BE19 Q24655139-234F82E3-2E1E-4D9F-B444-8E5AD636672F Q24683077-C6583981-82EE-4C96-B7C0-540BF5C9EDC7 Q24683783-EBA0D2E3-36F4-4B0E-83B4-1F3C8CF7930B Q26738430-EEABDCFB-A912-4F0F-8F39-0CE9301C54BD Q26765199-906F5C94-55EA-4A43-B6BF-2931DF79F1BE Q26768516-6539CEB2-C99F-4CCD-BDF8-70601F27587F Q26776412-69E2F775-255E-4F10-935C-D8F47BCFBBD1 Q26829435-0E1E1626-DDD4-42C5-B9A8-E0B8F93FE988 Q27316256-A93EF245-F476-4080-B7F2-0B79C88753F0 Q27654194-BF13CE80-83BD-4D40-B0A4-4D9ECB4CC3B9 Q27860822-D5EA4378-3B1F-4D0C-9F7E-2399AF6D9A62 Q27930894-4210B131-FFB0-46A5-A134-D00406DCD38D Q27932050-CB8F5165-F159-40F5-B35A-D36B3BB8D9BD Q27935325-9A68501E-AEB8-41F1-BE37-762E00FEB191 Q27937387-705B7B7B-5D0F-4E61-8012-679DCB45C262 Q28080090-437A8948-C546-4029-99F2-5F11B841A734 Q28117692-1DF4A733-A372-41FA-8B84-7837BD03C226 Q28255255-40BB9F5B-9762-4ED7-8FC6-771784BE458B Q28264111-07EF3FDD-ECD7-432C-A1FF-DE61033D0FD2 Q28504481-ABEBBD1E-0796-4FD6-A3D6-8279E7E1E86D Q28512412-3FA4C3B2-A443-4895-A26C-45B3D07554B1 Q28585480-17EF92AA-C172-4D4A-A8F9-B8236CF82419 Q28589906-1D2F8442-C8D2-44E0-B398-5B6D0796D11D Q28590435-FE15D3EF-D72B-474F-8A35-FBE9550BB660 Q28743694-67E39AC1-BF49-4CAC-909B-87D6EC5E9E35 Q29619777-879BEF46-C2B1-4CC9-918B-AA4BB6260800

P2860

Disruption of GW bodies impairs mammalian RNA interference

http://www.wikidata.org/entity/Q28281500

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Disruption of GW bodies impairs mammalian RNA interference

@ast

Disruption of GW bodies impairs mammalian RNA interference

@en

Disruption of GW bodies impairs mammalian RNA interference

@nl

type

label

Disruption of GW bodies impairs mammalian RNA interference

@ast

Disruption of GW bodies impairs mammalian RNA interference

@en

Disruption of GW bodies impairs mammalian RNA interference

@nl

prefLabel

Disruption of GW bodies impairs mammalian RNA interference

@ast

Disruption of GW bodies impairs mammalian RNA interference

@en

Disruption of GW bodies impairs mammalian RNA interference

@nl

P1433

Q28281500-298561B3-9F35-47E3-9A66-767BAA4DCCF6

P1476

Q28281500-046DDF06-31DB-4C02-99A4-10E2072AB480

P2093

Q28281500-18086A85-654D-4DF5-9812-E561E29D2AF6

Q28281500-34F2CE18-7492-4FCD-970C-C2478A895CDA

Q28281500-7215183E-835D-4B62-A069-57D2FF881433

Q28281500-A73F3F1E-D7FC-411A-AC1B-E007ACBC07CA

Q28281500-A8FCE4B9-C2AE-445A-B7DB-75D2CA9C5D7B

Q28281500-E7462BB2-914A-4A64-82CC-ABED503AF683

P2860

Q28281500-23E10B4C-7475-46C0-B8DB-247493140FE0

Q28281500-26660ECC-D3D7-42F5-8F41-754308A944BC

Q28281500-3614415C-0AE0-461E-BA98-82D56B4D521B

Q28281500-3A3A2DB5-199D-4F74-B95A-C88AC31FA254

Q28281500-4CA12E3D-7C5B-4E2F-A3E9-AA477AC526E4

Q28281500-51397010-5B88-4B3C-BCD9-F2EF6B06F387

Q28281500-5486D86C-3075-4409-A304-530EEDEC4D1F

Q28281500-5C885E76-5AB9-4EB8-9F47-119F48388592

Q28281500-6923EB2A-475B-4913-B6EC-3F371FD79F6D

Q28281500-6C5B7D3B-556B-48A2-84BA-8FB84A175769

P2888

Q28281500-5875EB60-9942-4524-9075-36E3AA5EB7E2

P304

Q28281500-8E53B709-29B7-4AAB-BF40-EADD1C7E2E05

P31

Q28281500-0B03A13D-C03C-400E-91EF-EE7939568099

P3181

Q28281500-709FD58B-31BC-4BD5-9CD4-BFA41829C648

P356

Q28281500-10574B11-DF35-4133-B962-2FE943A33DE9

P407

Q28281500-E72DCF83-ECE8-4D25-8BF2-E7FD7AE8F8FC

P433

Q28281500-D23627D0-217B-4541-A190-43DD3ADB0462

P478

Q28281500-E3B01193-A0DF-4428-B81A-A2694914762D

P50

Q28281500-7552E2B3-91FF-4695-9585-B3C96C62B5A0

Q28281500-FB9C1D9B-679F-4B6A-8C7E-D117F1F579C9

P577

Q28281500-9E756D45-75E5-4902-9771-99BC0D8FEEA8

P5875

Q28281500-DCA51F99-8F6B-4C20-9F94-B9D944EE0BA9

P6179

Q28281500-9F730DF6-5432-49FF-9366-BB6FED505A71

P698

Q28281500-72A90C56-7BB8-45DF-9D4C-6B554B62072B

P3181

P356

P1433

Nature Cell Biology

P1476

Disruption of GW bodies impairs mammalian RNA interference

@en

P2093

Andrew Jakymiw

http://www.w3.org/2001/XMLSchema#string

Edward K L Chan

http://www.w3.org/2001/XMLSchema#string

John C Hamel

http://www.w3.org/2001/XMLSchema#string

Shangli Lian

http://www.w3.org/2001/XMLSchema#string

Songqing Li

http://www.w3.org/2001/XMLSchema#string

Theophany Eystathioy

http://www.w3.org/2001/XMLSchema#string

P2860

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

Cytoplasmic foci are sites of mRNA decay in human cells

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

Argonaute2 is the catalytic engine of mammalian RNAi

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Decapping and decay of messenger RNA occur in cytoplasmic processing bodies

A microRNA in a multiple-turnover RNAi enzyme complex

P2888

P304

1267-74

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

385241

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NCB1334

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

Marvin J Fritzler

P577

2005-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7483060

http://www.w3.org/2001/XMLSchema#string

P6179

1002897804

http://www.w3.org/2001/XMLSchema#string

P698

16284622

http://www.w3.org/2001/XMLSchema#string