Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
about
Laminin receptor involvement in the anti-angiogenic activity of pigment epithelium-derived factorPigment epithelium-derived factor: clinical significance in estrogen-dependent tissues and its potential in cancer therapyPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesReceptor tyrosine kinases in the nucleusPEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseasesAnti-tumor effects of pigment epithelium-derived factor (PEDF): implication for cancer therapy. A mini-reviewPigment epithelium-derived factor (PEDF) as a therapeutic target in cardiovascular diseaseVEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model.A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature developmentComputational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport.A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trapAn antiangiogenic neurokinin-B/thromboxane A2 regulatory axisCodon preference optimization increases heterologous PEDF expression.Short pigment epithelial-derived factor-derived peptide inhibits angiogenesis and tumor growth.Overexpression of pigment epithelium-derived factor inhibits retinal inflammation and neovascularization.Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability.Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/beta-catenin signaling pathway and uPAR expression.PEDF regulates vascular permeability by a γ-secretase-mediated pathway.Hypertonic stress induces VEGF production in human colon cancer cell line Caco-2: inhibitory role of autocrine PGE₂γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathylet-7b and miR-126 are down-regulated in tumor tissue and correlate with microvessel density and survival outcomes in non--small--cell lung cancer.Pigment epithelial-derived factor (PEDF)-triggered lung cancer cell apoptosis relies on p53 protein-driven Fas ligand (Fas-L) up-regulation and Fas protein cell surface translocation.Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing's sarcoma.Soluble VEGFR-2: an antilymphangiogenic variant of VEGF receptors.Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.Elevated plasma levels of pigment epithelium-derived factor correlated with inflammation and lung function in COPD patientsN-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domainγ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of PreeclampsiaVascular endothelial growth factor receptor 1 morpholino decreases angiogenesis in a murine corneal suture model.MMP14 Cleavage of VEGFR1 in the Cornea Leads to a VEGF-Trap Antiangiogenic EffectRelease of soluble vascular endothelial growth factor receptor-1 (sFlt-1) during coronary artery bypass surgery.Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.Increased plasma levels of soluble vascular endothelial growth factor receptor 1 (sFlt-1) in women by moderate exercise and increased plasma levels of vascular endothelial growth factor in overweight/obese women.β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.Adenoviral E4 gene stimulates secretion of pigmental epithelium derived factor (PEDF) that maintains long-term survival of human glomerulus-derived endothelial cells
P2860
Q24644856-5C8DD073-1A91-4932-9F0D-90A6038DB79BQ26777495-9F5F1F11-89BC-408F-9608-1192B2A648D0Q26800956-A3060872-405E-4CBE-92D9-A23B09C92A07Q26830216-783E9F62-7795-4715-9566-07E5819B7AC4Q27026916-C2A11B49-5701-4BF2-8124-56975DCDC134Q28067001-285B6D10-FCD0-4CD4-9251-EB97252464CCQ28255757-76054EDB-54C7-457D-93AE-707C44D8E387Q30432040-A9EFA78E-7C95-4F7C-A757-BED93A9EC0BBQ30433214-533A40F6-E982-4A99-BA31-29A31D05E177Q30434991-B49ABFB3-81A4-41DE-8AC3-C2AB36C2B650Q30436024-9852B1CF-3785-42FB-B209-0AE798E04F89Q30439884-06782EDC-752A-4807-8085-1A7D470D2E86Q30480495-B4DF0C97-54B4-4FBC-BA82-0F7519C09A52Q33770029-4315A7AE-BFC9-4E4E-851C-95298200F0EEQ33789026-B724CB25-13F7-4C88-8615-5433E8624702Q33808055-627621FD-823E-4F63-866B-C11861BAF7E9Q33862606-D69C2CA1-3F9C-4067-9A1B-781105D7FE84Q33938310-A79746D9-9031-4047-9012-E0CD096FBA0BQ33939170-3B709665-D3A5-4F98-ABB7-4F104E36459DQ34042960-7728653C-093E-470F-A51A-2051777436B4Q34113394-3C5DABAC-BBE2-4E6F-B27F-21128E577C73Q34335696-9ECB26C3-D5A2-41C3-A79C-671A13529019Q34387956-0A34CA01-B350-4894-85DC-4982A49B9CBAQ34429485-7FBA491F-84AE-4FEF-8059-8060566C5E51Q34431110-1C6FB111-1F0E-41F5-BE87-505C0C9EE5E7Q34581539-982D26B0-A56B-4400-969E-43CA74FB05E5Q34631306-D6DC8313-7A88-4717-94CE-D06DB28447C6Q34706749-917A5507-CC4C-46AF-91CF-435CAA3B8876Q35027621-DB880ED9-FA64-4B3E-B56B-184D39B2873CQ35201511-F6C787EC-2353-4672-96CA-AC3CCFEE22C6Q35410651-5C102095-BCF4-4AA3-8DAC-300F32B98960Q35604861-CE049CDC-CB74-43DC-B04A-198F95E885DFQ35813842-D235A327-E7D7-4B81-9817-9F37D792D778Q35865416-A9A1D4F2-015F-4DEF-8EE5-9E55C2E54939Q35979968-63D98A72-6AC6-40BB-8AC4-8799377C5C31Q36083083-7CB9822C-88D5-4776-8A17-A69BB89C9F1EQ36113481-8D9DED28-85A9-4777-81CC-12FB9C4DB757Q36253217-C5DC6FD5-1E8D-4D30-90F2-09F8384D1751Q36379519-72758B6B-19B7-487C-8696-AF7EE4F9B2ECQ36386908-A85567FF-D8CF-4321-BF56-426EA8A5D28E
P2860
Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@ast
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@en
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@nl
type
label
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@ast
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@en
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@nl
prefLabel
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@ast
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@en
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@nl
P2093
P2860
P3181
P356
P1476
Pigment epithelium-derived fac ...... elial growth factor receptor 1
@en
P2093
Maria B Grant
Mike Boulton
Wen G Jiang
P2860
P304
P3181
P356
10.1074/JBC.M507401200
P407
P577
2006-02-10T00:00:00Z