In vivo half-life of a protein is a function of its amino-terminal residue
about
A tobacco etch virus protease with increased substrate tolerance at the P1' positionAlternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathwayCharacterization and chromosomal localization of USP3, a novel human ubiquitin-specific proteaseCDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3pA "housekeeping" gene on the X chromosome encodes a protein similar to ubiquitinA family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasomeThe yeast ubiquitin genes: a family of natural gene fusionsInhibition of the N-end rule pathway in living cellsThe N-end rule pathwayExtent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acidDiscovery of cellular regulation by protein degradationThe N-end rule: functions, mysteries, usesDistinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chainsCompilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAsThe human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamilyDiversity of degradation signals in the ubiquitin-proteasome systemNegative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase ISynthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathwayTargeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunizationDual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processingThe mouse and human genes encoding the recognition component of the N-end rule pathwayPheromone-regulated genes required for yeast mating differentiationAtaxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysisEnhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activityThe anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2Use of mRNA- and protein-destabilizing elements to develop a highly responsive reporter systemSNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPsDynamic covariation between gene expression and proteome characteristicsN-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule PathwayPerspectives and Insights into the Competition for Aminoacyl-tRNAs between the Translational Machinery and for tRNA Dependent Non-Ribosomal Peptide Bond FormationEthanol-induced oxidant stress modulates hepatic autophagy and proteasome activityN-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effectsMulticellularity makes somatic differentiation evolutionarily stable.Phenotypes on demand via switchable target protein degradation in multicellular organisms.Imaging complex protein metabolism in live organisms by stimulated Raman scattering microscopy with isotope labeling.Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prMStable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectorsHighly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication.
P2860
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P2860
In vivo half-life of a protein is a function of its amino-terminal residue
description
1986 nî lūn-bûn
@nan
1986 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
In vivo half-life of a protein is a function of its amino-terminal residue
@ast
In vivo half-life of a protein is a function of its amino-terminal residue
@en
In vivo half-life of a protein is a function of its amino-terminal residue
@nl
type
label
In vivo half-life of a protein is a function of its amino-terminal residue
@ast
In vivo half-life of a protein is a function of its amino-terminal residue
@en
In vivo half-life of a protein is a function of its amino-terminal residue
@nl
prefLabel
In vivo half-life of a protein is a function of its amino-terminal residue
@ast
In vivo half-life of a protein is a function of its amino-terminal residue
@en
In vivo half-life of a protein is a function of its amino-terminal residue
@nl
P3181
P356
P1433
P1476
In vivo half-life of a protein is a function of its amino-terminal residue
@en
P2093
A Varshavsky
P304
P3181
P356
10.1126/SCIENCE.3018930
P407
P50
P577
1986-10-10T00:00:00Z