Sirt1 activation by resveratrol is substrate sequence-selective - Test2 - elhamkhani - TriplyDB

Sirt1 activation by resveratrol is substrate sequence-selective

Sirt1 activation by resveratrol is substrate sequence-selective

http://www.wikidata.org/entity/Q28287726

about

Epigenetics and aging Sirtuin functions and modulation: from chemistry to the clinic Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds Synthesis and Assay of SIRT1-Activating Compounds Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules.Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation.Small-molecule allosteric activators of sirtuins.Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts.Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs Effect of Exercise Training on Skeletal Muscle SIRT1 and PGC-1α Expression Levels in Rats of Different Age.Targeting mutant p53 by a SIRT1 activator YK-3-237 inhibits the proliferation of triple-negative breast cancer cells Small molecule SIRT1 activators for the treatment of aging and age-related diseases.Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer New assays and approaches for discovery and design of Sirtuin modulators.Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement.Epigenetic pathway targets for the treatment of disease: accelerating progress in the development of pharmacological tools: IUPHAR Review 11.Metabolic effects of resveratrol: addressing the controversies.Growth factor, energy and nutrient sensing signalling pathways in metabolic ageing.Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application.BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development.Age-related loss of SirT1 expression results in dysregulated human vascular smooth muscle cell function.Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features.Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells.Biophysical characterization of hit compounds for mechanism-based enzyme activation.Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules Facile Synthesis of Cyclohexanediones and Dialkylresorcinols - Bioactive Natural Products from Entomopathogenic Bacteria

P2860

Q26740029-2ACD99CC-2191-40E7-8F65-C63B231A1847 Q26745884-90F7E56D-582A-4C68-8E77-A5711781BAA6 Q26747742-E772DC14-14EC-4DD8-8613-9D2623ED9C17 Q27679007-64FFAB3D-0898-40A6-86C7-4BD4F67B39A7 Q28314993-31955D34-EC81-4FA5-A177-BCAB19064289 Q28818352-C886FE79-9803-4449-868B-6FEF502D89EA Q30313597-05AFD0C8-397E-4DC7-B6F3-AAB4D9B68511 Q30830222-03918018-40FE-48D9-AB8B-F1265F78F9FD Q33601236-792C1486-AC25-443A-9C81-93F6410F299F Q33784452-69DE1F72-1061-4A78-8359-75B8A37F7878 Q35149578-6A556FE6-EC4E-48D0-B86F-5ED77B9FF010 Q35176143-25DA3CDA-59DD-44B1-AC1E-272FB1977FCB Q35550085-2F46E38B-7F24-4A78-8E7A-1B25C793917D Q35678633-AA225D59-D78D-4CA4-BCCE-963DB83B7792 Q35830011-1E9499DE-DD3B-403A-BD04-02694C02FB3F Q36048169-4246EFFA-E997-4C17-A092-FB08A6EE3C7F Q36792314-B95AC0E5-C805-499C-B1CB-187E9000E9FE Q37138538-BC1FB1E3-2A4B-4728-94C4-F247558F7F18 Q37673310-5D49E244-383D-4635-ADAE-5AB732B25502 Q37693464-08CC36E0-3C18-4010-B7B1-A7FFF85A50FC Q38175079-A5AC0701-0A31-402D-9C23-D113A85016B4 Q38188467-CA6F05E9-9624-4E8B-A91F-4B7947D6BC47 Q38233723-58D7985B-10A9-49DF-BCFC-3353D5171E29 Q38303686-DF4B3E18-5D07-46A1-B52F-662B97491970 Q38631149-189655A7-50FA-41CE-BD62-AC5E39278A68 Q38679237-1FD027C9-EEC3-426C-9766-F0515F382BCC Q38849159-FA4A6A82-10EC-482B-8F14-C55F30F11C26 Q44572962-7B04E573-DE39-452E-A404-FC6AA9545784 Q45947183-9FAA153D-1CD3-46BB-97CD-15704762269B Q47171465-E4207291-43E1-48BD-B38F-44896895064D Q48046295-AC13EDBD-0A8D-4227-8818-E956807D9F30 Q52652199-C86996C1-EC66-45B7-A22F-E16E4FB13225 Q56925925-2F296C7D-6BAF-4C96-9E6B-D9A8D08B878B Q58848386-A95962FC-1755-4115-8C0F-058300FCC6DE

P2860

Sirt1 activation by resveratrol is substrate sequence-selective

http://www.wikidata.org/entity/Q28287726

description

2013 nî lūn-bûn

@nan

2013 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի մարտին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Sirt1 activation by resveratrol is substrate sequence-selective

@ast

Sirt1 activation by resveratrol is substrate sequence-selective

@en

Sirt1 activation by resveratrol is substrate sequence-selective

@nl

type

label

Sirt1 activation by resveratrol is substrate sequence-selective

@ast

Sirt1 activation by resveratrol is substrate sequence-selective

@en

Sirt1 activation by resveratrol is substrate sequence-selective

@nl

prefLabel

Sirt1 activation by resveratrol is substrate sequence-selective

@ast

Sirt1 activation by resveratrol is substrate sequence-selective

@en

Sirt1 activation by resveratrol is substrate sequence-selective

@nl

P1433

Q28287726-B41149C2-1020-42C8-81F8-2A4B9AED8125

P1476

Q28287726-B5C7C7A4-78A0-48AD-9FB6-4BBB1BC8BE46

P2093

Q28287726-59FDA0B4-6A2E-403D-BFA0-51A9AD52A403

Q28287726-7C963757-4F37-4095-8006-1C7E209652B6

Q28287726-A0802B7B-85E1-415A-AE85-36F146454291

P2860

Q28287726-1718C8E6-DE17-4BDC-83F2-C64E985EFB1D

Q28287726-1CF7CE63-0BE8-4CA3-88B9-1D8EDA24B8ED

Q28287726-2393CD83-72E9-4135-B29F-2F6044208433

Q28287726-434E6158-CDF4-49D6-99AB-6CD7503238F8

Q28287726-489052DE-AEA8-4D2A-88AD-D0854BB6ACAD

Q28287726-61058705-D801-46DD-9258-B57A68B2C1EA

Q28287726-634B0B19-05B9-47FB-9E7F-C9D206D7ED8F

Q28287726-68820420-D7EE-457D-8219-C5EB908C8345

Q28287726-779B6DF9-3836-4481-B933-DB935E5AF82D

Q28287726-9B784F90-6B2A-429F-B674-2C76E384F4E0

P304

Q28287726-89907F16-158C-4721-878A-0FA2A5B3505E

P31

Q28287726-1ED99D1A-9D3D-4F9E-88CD-FE6B5F775F85

P3181

Q28287726-00BA4B3B-C561-45BD-B391-D0224D8FEFAE

P356

Q28287726-19107AD6-3EB7-4E0B-AA68-F83ADDDE7021

P407

Q28287726-591B6E52-E297-4762-B2D1-B399F577314C

P433

Q28287726-930AE82F-02DD-4340-98AB-F3541BF7417C

P478

Q28287726-24121664-7513-4D8F-8DE3-465A6CD0DC56

P50

Q28287726-A8E14F49-0C9E-43E1-A573-03094CF9220F

P577

Q28287726-C3785B67-DD99-45F2-A1D7-3F4A707913DF

P698

Q28287726-756508C9-A686-47E3-89C4-0B674BB1C22C

P932

Q28287726-91A22583-3B1F-4212-9CB5-3E7B74D10817

P3181

P356

P1433

P1476

Sirt1 activation by resveratrol is substrate sequence-selective

@en

P2093

Clemens Steegborn

http://www.w3.org/2001/XMLSchema#string

David Rauh

http://www.w3.org/2001/XMLSchema#string

Mahadevan Lakshminarasimhan

http://www.w3.org/2001/XMLSchema#string

P2860

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Resveratrol improves health and survival of mice on a high-calorie diet

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Mechanism of human SIRT1 activation by resveratrol

Resveratrol is not a direct activator of SIRT1 enzyme activity

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

Substrate-specific activation of sirtuins by resveratrol

Therapeutic potential of resveratrol: the in vivo evidence

P304

151-4

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1374449

http://www.w3.org/2001/XMLSchema#string

P356

10.18632/AGING.100542

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Mike Schutkowski

P577

2013-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23524286

http://www.w3.org/2001/XMLSchema#string

P932

3629287

http://www.w3.org/2001/XMLSchema#string