Regulation and expression of the adaptive response to alkylating agents
about
Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicalsCrystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNAIsolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanineCloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomereDefective processing of methylated single-stranded DNA by E. coli AlkB mutantsA non-heme iron-mediated chemical demethylation in DNA and RNAMutS inhibits RecA-mediated strand transfer with methylated DNA substrates.Ada response - a strategy for repair of alkylated DNA in bacteriaDNA bending and a flip-out mechanism for base excision by the helix–hairpin–helix DNA glycosylase, Escherichia coli AlkAConformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342Structural and Mutational Analysis of Escherichia coli AlkB Provides Insight into Substrate Specificity and DNA Damage SearchingCrystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coliReplication protein A binds to regulatory elements in yeast DNA repair and DNA metabolism genesCloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene.The Saccharomyces cerevisiae MGT1 DNA repair methyltransferase gene: its promoter and entire coding sequence, regulation and in vivo biological functions.Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli.Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repairRegulatory responses of the adaptive response to alkylation damage: a simple regulon with complex regulatory featuresIncreased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferaseMGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studiesCloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferaseSeparation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genesDetection of DNA damage by use of Escherichia coli carrying recA'::lux, uvrA'::lux, or alkA'::lux reporter plasmids.Point mutations at multiple sites including highly conserved amino acids maintain activity, but render O6-alkylguanine-DNA alkyltransferase insensitive to O6-benzylguanine.Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase.Novel AlkB dioxygenases--alternative models for in silico and in vivo studiesThe solution structure of the methylated form of the N-terminal 16-kDa domain of Escherichia coli Ada protein.Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase.Direct assay for O6-methylguanine-DNA methyltransferase and comparison of detection methods for the methylated enzyme in polyacrylamide gels and electroblots.Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha.Purification to homogeneity and partial amino acid sequence of a fragment which includes the methyl acceptor site of the human DNA repair protein for O6-methylguanineTranscriptome and proteome analyses of adaptive responses to methyl methanesulfonate in Escherichia coli K-12 and ada mutant strains.Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylationInfluence of alkyltransferase activity and chromosomal locus on mutational hotspots in Chinese hamster ovary cells.Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agentDepletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli.
P2860
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P2860
Regulation and expression of the adaptive response to alkylating agents
description
1988 nî lūn-bûn
@nan
1988 թուականին հրատարակուած գիտական յօդուած
@hyw
1988 թվականին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Regulation and expression of the adaptive response to alkylating agents
@ast
Regulation and expression of the adaptive response to alkylating agents
@en
Regulation and expression of the adaptive response to alkylating agents
@nl
type
label
Regulation and expression of the adaptive response to alkylating agents
@ast
Regulation and expression of the adaptive response to alkylating agents
@en
Regulation and expression of the adaptive response to alkylating agents
@nl
prefLabel
Regulation and expression of the adaptive response to alkylating agents
@ast
Regulation and expression of the adaptive response to alkylating agents
@en
Regulation and expression of the adaptive response to alkylating agents
@nl
P2093
P1476
Regulation and expression of the adaptive response to alkylating agents
@en
P2093
B Sedgwick
M Sekiguchi
Y Nakabeppu
P304
P356
10.1146/ANNUREV.BI.57.070188.001025
P407
P577
1988-01-01T00:00:00Z