Engineering GPCR signaling pathways with RASSLs - Test2 - elhamkhani - TriplyDB

Engineering GPCR signaling pathways with RASSLs

Engineering GPCR signaling pathways with RASSLs

http://www.wikidata.org/entity/Q28289158

about

Therapeutic Strategies for Neuropathic Pain: Potential Application of Pharmacosynthetics and Optogenetics Synthetic biology approaches to engineer T cells New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors DREADDs: novel tools for drug discovery and development Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits Preclinical models for obesity research Pharmacosynthetics: Reimagining the pharmacogenetic approach Structure and function of serotonin G protein-coupled receptors.Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia.Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders.Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells Inducible and titratable silencing of Caenorhabditis elegans neurons in vivo with histamine-gated chloride channels Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs.Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling Eukaryotic systems broaden the scope of synthetic biology.Muscarinic control of MIN6 pancreatic β cells is enhanced by impaired amino acid signaling.Rational Redesign of a Functional Protein Kinase-Substrate Interaction.Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation Molecular genetics and imaging technologies for circuit-based neuroanatomy.Cell-type specific regulation of cortical excitability through the allatostatin receptor system.Modular extracellular sensor architecture for engineering mammalian cell-based devices.Biology by design: from top to bottom and back Transgenic mice: beyond the knockout Structure-based approaches to ligands for G-protein-coupled adenosine and P2Y receptors, from small molecules to nanoconjugates.Transient neuronal inhibition reveals opposing roles of indirect and direct pathways in sensitization Remote control of neuronal signaling.Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation.A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.Striatal microcircuitry and movement disorders Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice.Modulating and evaluating receptor promiscuity through directed evolution and modeling.A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.DREADDs for Neuroscientists.Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptors

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P2860

Engineering GPCR signaling pathways with RASSLs

http://www.wikidata.org/entity/Q28289158

description

2008 nî lūn-bûn

@nan

2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Engineering GPCR signaling pathways with RASSLs

@ast

Engineering GPCR signaling pathways with RASSLs

@en

Engineering GPCR signaling pathways with RASSLs

@nl

type

label

Engineering GPCR signaling pathways with RASSLs

@ast

Engineering GPCR signaling pathways with RASSLs

@en

Engineering GPCR signaling pathways with RASSLs

@nl

prefLabel

Engineering GPCR signaling pathways with RASSLs

@ast

Engineering GPCR signaling pathways with RASSLs

@en

Engineering GPCR signaling pathways with RASSLs

@nl

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P1476

Engineering GPCR signaling pathways with RASSLs

@en

P2093

Aline Dumuis

http://www.w3.org/2001/XMLSchema#string

Bruce R Conklin

http://www.w3.org/2001/XMLSchema#string

Bryan L Roth

http://www.w3.org/2001/XMLSchema#string

Edward C Hsiao

http://www.w3.org/2001/XMLSchema#string

Jean-Marc Guettier

http://www.w3.org/2001/XMLSchema#string

John R Forsayeth

http://www.w3.org/2001/XMLSchema#string

Jürgen Wess

http://www.w3.org/2001/XMLSchema#string

Ken D McCarthy

http://www.w3.org/2001/XMLSchema#string

Robert A Nissenson

http://www.w3.org/2001/XMLSchema#string

Supriya Srinivasan

http://www.w3.org/2001/XMLSchema#string

P2860

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Controlling signaling with a specifically designed Gi-coupled receptor

Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

The receptors and coding logic for bitter taste

Allele-specific activation of genetically engineered receptors

Drugs and valvular heart disease

Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor

The druggable genome

P2888

P304

673-8

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scholarly article

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10.1038/NMETH.1232

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8

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P478

5

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23138432

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1044874264

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P698

18668035

http://www.w3.org/2001/XMLSchema#string

P921

G protein-coupled receptor

P932

2703467

http://www.w3.org/2001/XMLSchema#string