The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65
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Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skinLeptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved regionA refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slicesErgolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaBReconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamianaGentiolactone, a secoiridoid dilactone from Gentiana triflora, inhibits TNF-α, iNOS and Cox-2 mRNA expression and blocks NF-κB promoter activity in murine macrophagesEvidence for the ancient origin of the NF-kappaB/IkappaB cascade: its archaic role in pathogen infection and immunityCharting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase IIAnti-inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensisDeoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in mice.The CO donor CORM-2 inhibits LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts.Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNACombinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic CompoundsNF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell deathSPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signalingDelayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065.Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.NF-κB repressing factor inhibits chemokine synthesis by peripheral blood mononuclear cells and alveolar macrophages in active pulmonary tuberculosisSynthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway.Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes.VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors.Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharidesValidation of analytical procedures using HPLC-ELSD to determine six sesquiterpene lactones in Eremanthus species.Parthenolide induces apoptosis in colitis-associated colon cancer, inhibiting NF-κB signaling.Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB.Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.The effect of dehydroleucodine in adipocyte differentiation.Rel A/p65 is required for cytokine-induced myotube atrophy.Expression profiling identifies epoxy anthraquinone derivative as a DNA topoisomerase inhibitor.NFkappaB in neurons? The uncertainty principle in neurobiologyIdentification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death.Helenalin-mediated post-transcriptional regulation of p21(Cip1) inhibits 3T3-L1 preadipocyte proliferationSesquiterpenoids lactones: benefits to plants and people.Ouabain protects against Shiga toxin-triggered apoptosis by reversing the imbalance between Bax and Bcl-xL.Effects of budlein A on human neutrophils and lymphocytes.Loss of IKKbeta activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosisCox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS ExpressionChemical biology of inflammatory cytokine signaling.
P2860
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P2860
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@ast
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@en
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@nl
type
label
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@ast
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@en
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@nl
prefLabel
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@ast
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@en
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@nl
P2093
P3181
P356
P1476
The anti-inflammatory sesquite ...... ppaB by directly targeting p65
@en
P2093
P304
33508-33516
P3181
P356
10.1074/JBC.273.50.33508
P407
P577
1998-12-01T00:00:00Z