RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
about
Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyMolecular crosstalk between apoptosis, necroptosis, and survival signalingPoly-ubiquitination in TNFR1-mediated necroptosisAn outline of necrosome triggersUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisDepletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosisNoncanocial cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1.Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLMK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.Programmed cell death and its role in inflammationInsights into battles between Mycobacterium tuberculosis and macrophages.The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunityTAK1 control of cell death.Programmed necrosis in inflammation: Toward identification of the effector molecules.Regulated cell death in AKI.Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodelingB-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics.Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production.Brain endothelial TAK1 and NEMO safeguard the neurovascular unitEndoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cellsCharacterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis.Activation of necroptosis in human and experimental cholestasis.TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints.RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosisTAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation.RIPK1 protects from TNF-α-mediated liver damage during hepatitis.RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome.Necrosis-dependent and independent signaling of the RIP kinases in inflammation.TAK1 regulates hepatic cell survival and carcinogenesis.Ars Moriendi; the art of dying well - new insights into the molecular pathways of necroptotic cell death.TAK1 selective inhibition: state of the art and future opportunities.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.Death receptor 3 mediates necroptotic cell death.SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.A real-time fluorometric method for the simultaneous detection of cell death type and rate.
P2860
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P2860
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@ast
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@en
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@nl
type
label
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@ast
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@en
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@nl
prefLabel
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@ast
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@en
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@nl
P2093
P2860
P3181
P356
P1476
RIPK3 contributes to TNFR1-med ...... tion or TAK1 kinase inhibition
@en
P2093
C Dubuisson
E Dejardin
M A Aguileta
M J M Bertrand
V Goossens
Y Dondelinger
P2860
P2888
P304
P3181
P356
10.1038/CDD.2013.94
P407
P577
2013-10-01T00:00:00Z