IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
about
Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathwayAn atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitinationSmac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosisIAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationRIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosisCellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcriptionIdentification of a novel protein kinase Cδ-Smac complex that dissociates during paclitaxel-induced cell deathcIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoformsThe USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2OTUB1 modulates c-IAP1 stability to regulate signalling pathwaysPellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-αIs NF-kappaB a good target for cancer therapy? Hopes and pitfallsc-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activationDivalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neuronsTargeting Cell Survival Proteins for Cancer Cell DeathRegulation of Cell Death by IAPs and Their AntagonistsDED or alive: assembly and regulation of the death effector domain complexesNF-κB, the first quarter-century: remarkable progress and outstanding questionsInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationWhen ubiquitin meets NF-κB: a trove for anti-cancer drug developmentFueling the flames: Mammalian programmed necrosis in inflammatory diseasesThe two faces of receptor interacting protein kinase-1Small-molecule SMAC mimetics as new cancer therapeuticsApoptotic agentsTargeting the apoptosis pathway in hematologic malignanciesNon-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple JuncturesRIPK-dependent necrosis and its regulation by caspases: a mystery in five actsProgrammed necrosis in the cross talk of cell death and inflammationStructures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitmentStructural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and RegulationRecognition of Smac-mimetic compounds by the BIR domain of cIAP1Antagonists induce a conformational change in cIAP1 that promotes autoubiquitinationRegulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligaseThe deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosisTargeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell LymphomaRegulation of tumour necrosis factor signalling: live or let dieNF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppressionRIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibitionSmac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathway
P2860
Q21245702-CB0CAD1D-AB4A-4C6D-BBBE-D4052460A58CQ24294345-B40B3540-B7DC-4EEF-A667-41728EC22690Q24294685-5D89B6C5-BEB5-4236-ACB1-E5FBF4A09DE1Q24298339-4B420031-E291-4EA7-B6B3-E7E346031736Q24299986-02B69503-D8D2-4C2E-AFE7-6FF898D08ECCQ24306110-C7A22D7A-6C71-4B1E-B9EB-27578933E55AQ24310544-EC0F222D-4243-4B28-9A21-43D1CB58F328Q24311676-967860D4-2564-4F96-8994-739C7B9DD36EQ24323126-B6CD3B1A-E2FB-4F4A-8077-A7CF110F63ACQ24337266-6A242BC8-3A3B-4C35-96B9-48D1F87D01A6Q24338172-5B9241A4-B0E3-41B2-8B4F-EFA0772F4E0AQ24570128-009C90CA-F1F2-4363-B6E5-270FD9BADB77Q24607621-3F360234-0625-4EDA-9C50-5C2DA5080D8AQ24657218-7A54A996-8BDF-4176-9451-A79A4F989610Q26765447-BE01CD52-F38D-43B7-95EC-27F4D7F08B1DQ26782579-7681CA41-FAE0-4560-90D2-EFB12CD4799DQ26796544-DEF1A112-3B26-4EAE-9406-E1D97A7F86A6Q26822516-1BE9DECB-6E9F-402F-9272-5604C1EAE830Q26824586-DCB5EA45-DFCE-4B62-9242-2F87F09EA5AFQ26827754-0DFFC554-C29E-4B17-916B-A5868EB20E15Q26830515-FA713695-D946-4169-A966-0659ADF43E8FQ26853682-013D17C4-90BC-45CC-9DEB-BB9F9EF72B43Q26864204-B11CEECD-FB0F-42C8-8602-DD1C858E1C4EQ27016160-CDE7C62C-AA51-4F3F-BC7C-1813FE66295EQ27024422-F8F052CE-E881-47DE-B192-73918DC241B4Q27024640-4C378BB5-C72E-41DF-A0B9-DFC2A0035CAAQ27026600-17276038-7AE7-48C4-BF93-5C9D81ABA825Q27026709-0B2A60B6-AC67-4D5C-8C9D-965522FE720DQ27652077-8FA294DF-0556-4935-B864-8D2BF30E9FD9Q27657715-0BB0A269-D8E5-48CC-AC56-56A816EA886DQ27660497-328E5859-77C8-492A-94F8-6C37E457E813Q27665119-93B8D782-D059-4359-A842-35503C6BDC9FQ27675192-6A71E978-98A3-4456-AE74-ABF18D4A49DDQ27683623-C08DCC8C-35E7-4192-854A-C444B999F748Q28115594-D89783AD-AF89-4F25-AA88-34D56369DD36Q28115962-8C16AAF8-8E21-4A4D-9E3B-7A2B7CE5F17BQ28262381-2294927B-2883-4A18-94A2-7857F585E16CQ28268202-3E167D7D-5F92-4B7B-B558-1CCCB870D2A7Q28295435-45523B47-2CBC-4870-A21D-EE3AD1CA9C47Q28303498-1317799A-B48F-4E98-ACEA-65BCD32EE4E7
P2860
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@ast
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en-gb
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@nl
type
label
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@ast
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en-gb
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@nl
prefLabel
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@ast
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en-gb
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@nl
P2093
P50
P921
P3181
P1433
P1476
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
@en
P2093
Bernard A Callus
Christopher A Benetatos
Frank Koentgen
James E Vince
Mark McKinlay
Martin Leverkus
Nufail Khan
Rebecca Feltham
Robert Brink
P304
P3181
P356
10.1016/J.CELL.2007.10.037
P407
P577
2007-11-01T00:00:00Z