The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus
about
Mouse Genetic Models of Human Brain DisordersDlx transcription factors promote migration through repression of axon and dendrite growthp21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesisThe Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptorsp21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic propertiesRescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutationsExcess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disabilityIdentification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.Identification of phosphorylation sites in betaPIX and PAK1PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth.Ras and Rap signaling in synaptic plasticity and mental disorders.Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression.PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and AβAbnormal Development of Dendrites in Adult-Born Rat Hippocampal Granule Cells Induced by Cyclophosphamide.Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome.Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.Intellectual disability and autism spectrum disorders: causal genes and molecular mechanisms.Structural plasticity: mechanisms and contribution to developmental psychiatric disordersGenetics and pathophysiology of mental retardation.An APPL1/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neuronsDendritic spine dynamics--a key role for kalirin-7.Lethality of PAK3 and SGK2 shRNAs to human papillomavirus positive cervical cancer cells is independent of PAK3 and SGK2 knockdownPAK1 as a therapeutic target.p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptorPalmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity.PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neuronsDendritic spines and long-term plasticity.The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathwaysTuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPPCell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-lossHippocampal CA1 pyramidal neurons of Mecp2 mutant mice show a dendritic spine phenotype only in the presymptomatic stage.Dbo/Henji Modulates Synaptic dPAK to Gate Glutamate Receptor Abundance and Postsynaptic Response.Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development.The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.Rho-linked genes and neurological disorders.Characterization of oligophrenin-1, a RhoGAP lost in patients affected with mental retardation: lentiviral injection in organotypic brain slice cultures.Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.Sudden death in toddlers associated with developmental abnormalities of the hippocampus: a report of five cases.
P2860
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P2860
The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The mental retardation protein ...... and plasticity in hippocampus
@ast
The mental retardation protein ...... and plasticity in hippocampus
@en
The mental retardation protein ...... and plasticity in hippocampus
@nl
type
label
The mental retardation protein ...... and plasticity in hippocampus
@ast
The mental retardation protein ...... and plasticity in hippocampus
@en
The mental retardation protein ...... and plasticity in hippocampus
@nl
prefLabel
The mental retardation protein ...... and plasticity in hippocampus
@ast
The mental retardation protein ...... and plasticity in hippocampus
@en
The mental retardation protein ...... and plasticity in hippocampus
@nl
P2093
P3181
P1476
The mental retardation protein ...... and plasticity in hippocampus
@en
P2093
Bernadett Boda
Dominique Muller
Irina Nikonenko
Lorena Parisi-Jourdain
Marlyse Moosmayer
Pascal Jourdain
Roxanne Node-Langlois
Stefano Alberi
P304
10816-10825
P3181
P356
10.1523/JNEUROSCI.2931-04.2004
P407
P577
2004-12-01T00:00:00Z