JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
about
Targeting c-Jun and JunB proteins as potential anticancer cell therapySyntenic relationships between genomic profiles of fiber-induced murine and human malignant mesotheliomaTriptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expressionGlobal gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancerFunctional copy-number alterations in cancer.c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesisEmerging roles of ATF2 and the dynamic AP1 network in cancer.DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies.A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cellsAn experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors.Predicting dedifferentiation in liposarcoma: a proteomic approach.Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.Advances in the targeted therapy of liposarcoma.Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma.Retroperitoneal liposarcoma: current insights in diagnosis and treatmentAdipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy.Retroviral cyclin controls cyclin-dependent kinase 8-mediated transcription elongation and reinitiation.Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas.c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomasAplidin in patients with advanced dedifferentiated liposarcomas: a French Sarcoma Group Single-Arm Phase II studyCopy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.Multiple sites of highly amplified DNA sequences detected by molecular cytogenetic analysis in HS-RMS-2, a new pleomorphic rhabdomyosarcoma cell lineC-Jun recruits the NSL complex to regulate its target gene expression by modulating H4K16 acetylation and promoting the release of the repressive NuRD complexAdvances in sarcoma genomics and new therapeutic targets.HP1a/KDM4A is involved in the autoregulatory loop of the oncogene gene c-Jun.Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer.Biological characterization of soft tissue sarcomasRegulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk.Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibitionThe oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy.Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival.Understanding signaling cascades in melanomaSystems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules.De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes.Molecular mechanisms of uterine leiomyosarcomas: involvement of defect in LMP2 expression.G protein pathway suppressor 2 (GPS2) acts as a tumor suppressor in liposarcoma.Chromosomal changes in aggressive breast cancers with basal-like features.Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management.Frequent amplification of receptor tyrosine kinase genes in welldifferentiated/ dedifferentiated liposarcoma.
P2860
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P2860
JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
JUN oncogene amplification and ...... in highly aggressive sarcomas
@ast
JUN oncogene amplification and ...... in highly aggressive sarcomas
@en
JUN oncogene amplification and ...... in highly aggressive sarcomas
@nl
type
label
JUN oncogene amplification and ...... in highly aggressive sarcomas
@ast
JUN oncogene amplification and ...... in highly aggressive sarcomas
@en
JUN oncogene amplification and ...... in highly aggressive sarcomas
@nl
prefLabel
JUN oncogene amplification and ...... in highly aggressive sarcomas
@ast
JUN oncogene amplification and ...... in highly aggressive sarcomas
@en
JUN oncogene amplification and ...... in highly aggressive sarcomas
@nl
P2093
P3181
P1433
P1476
JUN oncogene amplification and ...... in highly aggressive sarcomas
@en
P2093
Alain Aurias
Carine Ganem
Caroline Brennetot
Jean-Michel Coindre
Nadège Gruel
Odette Mariani
P304
P3181
P356
10.1016/J.CCR.2007.02.007
P407
P577
2007-04-01T00:00:00Z