Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells - Test2 - elhamkhani - TriplyDB

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

http://www.wikidata.org/entity/Q28298650

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Insights into APC/C: from cellular function to diseases and therapeutics Metabolomics in rheumatic diseases: desperately seeking biomarkers Recent insights into the role of autophagy in the pathogenesis of rheumatoid arthritis Powering the immune system: mitochondria in immune function and deficiency T-cell aging in rheumatoid arthritis Regulators of autophagosome formation in Drosophila muscles Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping Rheumatoid Arthritis, Immunosenescence and the Hallmarks of Aging Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.Autophagy and the immune function in aging Pharmacological regulators of autophagy and their link with modulators of lupus disease T-cell metabolism in autoimmune disease.Autophagy in autoimmune disease Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.Targets of immune regeneration in rheumatoid arthritis.Cutting Edge: Increased Autoimmunity Risk in Glycogen Storage Disease Type 1b Is Associated with a Reduced Engagement of Glycolysis in T Cells and an Impaired Regulatory T Cell Function.Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells.Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation Mincle-mediated translational regulation is required for strong nitric oxide production and inflammation resolution.A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22 Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis.The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.The Autophagy Level Is Increased in the Synovial Tissues of Patients with Active Rheumatoid Arthritis and Is Correlated with Disease Severity.Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes.Cellular and metabolic functions for autophagy in cancer cells.Elevated TRAF4 expression impaired LPS-induced autophagy in mesenchymal stem cells from ankylosing spondylitis patients Metabolic control of arthritis: Switch pathways to treat.T-cell metabolism governing activation, proliferation and differentiation; a modular view.Immunometabolism and autoimmunity.Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis.Lactate at the crossroads of metabolism, inflammation, and autoimmunity.Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence.Successful and Maladaptive T Cell Aging.Metabolic regulation of inflammation.Immunometabolism in early and late stages of rheumatoid arthritis.Fine tuning of immunometabolism for the treatment of rheumatic diseases.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Metabolic signatures of T-cells and macrophages in rheumatoid arthritis.

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Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

http://www.wikidata.org/entity/Q28298650

description

2013 nî lūn-bûn

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2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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Journal of Experimental Medicine

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Phosphofructokinase deficiency ...... n rheumatoid arthritis T cells

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P2093

Cornelia M Weyand

http://www.w3.org/2001/XMLSchema#string

Hiroshi Fujii

http://www.w3.org/2001/XMLSchema#string

Jorg J Goronzy

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Shalini V Mohan

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Zhen Yang

http://www.w3.org/2001/XMLSchema#string

P2860

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Understanding the Warburg effect: the metabolic requirements of cell proliferation

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

On the Origin of Cancer Cells

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases

The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells

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2119-34

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scholarly article

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100968

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10.1084/JEM.20130252

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10

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210

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2013-09-23T00:00:00Z

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256666573

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24043759

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3782046

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