6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis - Test2 - elhamkhani - TriplyDB

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

http://www.wikidata.org/entity/Q24528111

about

Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)Energy metabolism in the liver Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells PFKFB3 Regulates Oxidative Stress Homeostasis via Its S-Glutathionylation in Cancer Heterogeneity of glycolysis in cancers and therapeutic opportunities.A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast.Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells Energy metabolism in tumor cells Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats Dimer interface rearrangement of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase rat liver isoenzyme by cAMP-dependent Ser-32 phosphorylation Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasis The control systems structures of energy metabolism.Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.Blood glucose regulation during prolonged, submaximal, continuous exercise: a guide for clinicians.A novel β-glucosidase with lipolytic activity from a soil metagenome.Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation.PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli.Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation.MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.Structure-based design of small-molecule ligands of phosphofructokinase-2 activating or inhibiting glycolysis.TIGAR regulates glycolysis in ischemic kidney proximal tubules.Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.An insertion of intracisternal A-particle retrotransposon in a novel member of the phosphoglycerate mutase family in the lew allele of mutant mice Investigating combinatorial approaches in virtual screening on human inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3): a case study for small molecule kinases.A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians.Organismal carbohydrate and lipid homeostasis.Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.Diabetic vascular disease and the potential role of macrophage glucose metabolism Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways.Anticancer agents that counteract tumor glycolysis.3-bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial-mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth.Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response.Nutrient sensing and utilization: Getting to the heart of metabolic flexibility.

P2860

Q24315699-883462F9-89EA-4D4E-AAA9-B254744B4D87 Q26996783-D51E7A17-E34D-45C4-9565-F31320D0C06B Q27014979-301D8A80-8148-4BFE-A168-300E092774C4 Q27680730-1F6CAB60-1BDB-4D17-800F-D41C54696013 Q27693375-E0FA5734-2B9F-4BEF-9D0E-02944F701C8B Q27934919-37950779-3AD0-4393-AC62-FA83B469C79B Q28253893-6CDD43BD-4FDE-42DF-AA5C-755686D1EDC4 Q28288377-50A28BD3-A632-4E4A-B2B7-FA97F085CE82 Q28298650-1D54B1DB-910F-438B-938A-071A93CE918A Q28477166-C009CCF0-F289-4736-9136-30862A223BCE Q28565224-1ADDCBA0-8465-4B73-9EC0-C1474E500322 Q28579035-9294899C-930B-4866-AF16-D927924C9376 Q30928926-0BB33678-C224-403C-98BE-8E1501222F9B Q31149649-D4F430F4-7A85-4444-AA29-9B64840B135F Q33662075-85700D4F-CE20-46CA-97DF-A2CC32EB81B7 Q33676546-5B5C23A0-796A-426A-8362-B3D3D4FDBB38 Q33743313-0E36400F-6E54-4E73-A697-3C051DE08B9B Q33752121-41857E6E-D55E-4D9C-AEBD-9A6F180A7BF5 Q33979757-A0500B59-A008-4D81-8869-6469D12B1029 Q34083594-035E1312-CBC8-45B0-BD14-EF9E73354E5F Q34231660-6FA265D4-AA9C-4928-AD19-2440C32B9052 Q34271644-911ED61C-C1AD-420D-8C11-E601D7153452 Q34336533-D9FD2F0F-E623-4BF0-BE3A-17B9D7CAE488 Q34357440-92826231-5AAA-4FB2-A8D5-A72C96A9768A Q34388808-1C70AA2B-6C50-4857-ACFD-0D4BC5F277A4 Q34485139-60909F35-DC45-4695-A8C5-B56EC7604465 Q34787536-B43AF23A-E35D-403F-B816-D267A5335EE9 Q35086457-C391AA43-6AE5-4EC6-B479-AD2449B7CE7D Q35087457-F3259AEA-ED38-4590-BB93-849B9911B38A Q35163989-3DF3A87D-4CF7-4DA6-9A01-56D5BAA4153C Q35194079-0170482B-CC38-4817-AEBB-2AF601C0178A Q35558848-D7839583-8A65-4651-97F1-EAD3E466229D Q35902714-AF6EB71F-16BC-4E3F-9BF5-056F02DBA90B Q36033307-80BE94B3-3CE8-43D7-967D-2C3DFDFD61AF Q36199128-AE9169A9-501E-476A-94DD-8267E468C66F Q36396560-9ACBCF5F-3A48-45F6-A3AA-CF5CD6013B42 Q36452381-6340841A-06BF-4824-A86F-7CE4F580F1D0 Q36572127-7A1C2198-09F7-4D39-8A37-35CE49EC2E28 Q36644432-DF75ED7B-413A-4E1A-97C0-E79BC5CDAA54 Q36788620-98B0E004-25F5-4B0E-95F2-F806AE41BCB8

P2860

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

http://www.wikidata.org/entity/Q24528111

description

2004 nî lūn-bûn

@nan

2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@ast

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en-gb

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@nl

type

label

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@ast

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en-gb

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@nl

prefLabel

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@ast

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en-gb

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@nl

P1433

Q24528111-22C9E078-C6B9-4D48-8B62-0829F2F64662

P1476

Q24528111-A07DE33A-A1DD-4FA7-A648-50919B7CBF87

P2093

Q24528111-28EA26F8-81DA-4772-A69C-45860E099024

Q24528111-33DD3E26-F0FD-44B9-A3AD-A2A38BB89934

Q24528111-5B8AFB52-B6C7-4AC2-9BFB-A8A907B37E29

Q24528111-9E4FCDCF-8C1B-4FC8-8B99-DC12DD258708

Q24528111-AA1E91CF-C854-4007-98AA-0C424A72CBAA

P2860

Q24528111-017642C7-BE0D-4179-BB09-758E1672CD4D

Q24528111-043C2C5C-D270-4137-8793-4D68F155DF92

Q24528111-053B99F7-C037-425A-A2A5-FFDB5CC2D60F

Q24528111-055844B2-E3F3-4D4F-AAD4-73090F5BB4CA

Q24528111-0803E7A4-B70E-4C2C-A7FD-AECD36969FB8

Q24528111-08299ECB-BC86-441C-AF4E-5200B5E3CE04

Q24528111-08DBD502-2B6F-41C3-9266-40277C2C6491

Q24528111-09A69412-BBA7-4F7F-907B-7E9F05CB2840

Q24528111-10BB878A-AEA1-47CB-A014-9574FE59B572

Q24528111-113D6BD4-4B83-47C9-9227-23035F41DF1A

P304

Q24528111-49A57D92-6876-44BC-B029-C2A77DD1B085

P31

Q24528111-1C84619C-3104-40DF-9ABD-16DD136390D3

P356

Q24528111-83334F27-845B-4C89-8E86-79EC4449C3A0

P407

Q24528111-0E68901C-A0AE-4D74-83B1-79438A94C0E2

P433

Q24528111-A29AA247-EC3F-43FC-BC8C-C2D044A6B366

P478

Q24528111-33C1945E-82FE-4E58-94DE-990A1B141AA8

P50

Q24528111-E5D0DED9-F9E0-4020-A54F-E0060C339C0C

P577

Q24528111-77344728-BBF1-4DC9-AB59-6F2D05500281

P5875

Q24528111-CFE05314-830C-4DF3-B0B0-9A844FA5DD43

P698

Q24528111-E7B2AB65-C8C8-445F-A662-05D0D274169C

P921

Q24528111-EACE4DF4-6D87-4123-A1A8-5543E8C938C5

P932

Q24528111-3DB358C3-5D4B-48AE-8C18-0195638C7E84

P356

P1433

Biochemical Journal

P1476

6-phosphofructo-2-kinase/fruct ...... nzyme that controls glycolysis

@en

P2093

Guy G Rousseau

http://www.w3.org/2001/XMLSchema#string

Louis Hue

http://www.w3.org/2001/XMLSchema#string

Luc Bertrand

http://www.w3.org/2001/XMLSchema#string

Mark H Rider

http://www.w3.org/2001/XMLSchema#string

Paul A Michels

http://www.w3.org/2001/XMLSchema#string

P2860

OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6

Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene

Enzyme-Catalyzed Phosphoryl Transfer Reactions

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

Insulin signalling and the regulation of glucose and lipid metabolism

Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta

Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

Sequence and structure of the human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform gene (PFKFB2)

P304

561-79

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1042/BJ20040752

http://www.w3.org/2001/XMLSchema#string

P407

P433

Pt 3

http://www.w3.org/2001/XMLSchema#string

P478

381

http://www.w3.org/2001/XMLSchema#string

P50

Didier Vertommen

P577

2004-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8537069

http://www.w3.org/2001/XMLSchema#string

P698

15170386

http://www.w3.org/2001/XMLSchema#string

P921

P932

1133864

http://www.w3.org/2001/XMLSchema#string