Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily
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Challenging Density Functional Theory Calculations with Hemes and PorphyrinsCrystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation StateThe 1.5-Å Structure of XplA-heme, an Unusual Cytochrome P450 Heme Domain That Catalyzes Reductive Biotransformation of Royal Demolition ExplosiveGlutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atomUnusual Spectroscopic and Ligand Binding Properties of the Cytochrome P450-Flavodoxin Fusion Enzyme XplAKey Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate BiasStructural Basis of Substrate Conversion in a New Aromatic Peroxygenase: CYTOCHROME P450 FUNCTIONALITY WITH BENEFITSThe crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding siteStructure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE(CYP152L1) from theJeotgalicoccussp. 8456 BacteriumHuman P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3The structure of a novel electron-transfer ferredoxin from Rhodopseudomonas palustris HaA2 which contains a histidine residue in its iron-sulfur cluster-binding motifEvaluation of influence of single nucleotide polymorphisms in cytochrome P450 2B6 on substrate recognition using computational docking and molecular dynamics simulationMolecular Dynamics Simulations to Investigate the Influences of Amino Acid Mutations on Protein Three-Dimensional Structures of Cytochrome P450 2D6.1, 2, 10, 14A, 51, and 62Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylaseNADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family.Structure and function of enzymes involved in the biosynthesis of phenylpropanoidsCYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in riceCharacterization of Cupriavidus metallidurans CYP116B1--a thiocarbamate herbicide oxygenating P450-phthalate dioxygenase reductase fusion protein.A gene-fusion approach to enabling plant cytochromes p450 for biocatalysis.Lincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family.Mechanism of S-oxygenation by a cysteine dioxygenase model complexSubstrate Hunting for the Myxobacterial CYP260A1 Revealed New 1α-Hydroxylated Products from C-19 Steroids.Reconstitution of the In Vitro Activity of the Cyclosporine-Specific P450 Hydroxylase from Sebekia benihana and Development of a Heterologous Whole-Cell Biotransformation System.Unusual properties of the cytochrome P450 superfamily.Unusual cytochrome p450 enzymes and reactions.Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects.New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners.The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention.P450(BM3) (CYP102A1): connecting the dots.Cholesterol, an essential molecule: diverse roles involving cytochrome P450 enzymes.The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications.Computational modelling of oxygenation processes in enzymes and biomimetic model complexes.Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations.Guidelines for development and implementation of biocatalytic P450 processes.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis.Photosynthetic fuel for heterologous enzymes: the role of electron carrier proteins.Enzymatic site-selectivity enabled by structure-guided directed evolution.
P2860
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P2860
Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@ast
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@en
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@nl
type
label
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@ast
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@en
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@nl
prefLabel
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@ast
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@en
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@nl
P2093
P2860
P3181
P356
P1476
Variations on a (t)heme--novel ...... he cytochrome P450 superfamily
@en
P2093
Andrew W Munro
Hazel M Girvan
Kirsty J McLean
P2860
P304
P3181
P356
10.1039/B604190F
P407
P577
2007-06-01T00:00:00Z