about
Structural and chemical profiling of the human cytosolic sulfotransferasesNicotinamide riboside kinase structures reveal new pathways to NAD+Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signalingStructural basis for selective binding of m6A RNA by the YTHDC1 YTH domainFirst crystallographic models of human TBC domains in the context of a family-wide structural analysisSgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.Structure and function of the intracellular region of the plexin-b1 transmembrane receptorIQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain foldA chemical probe selectively inhibits G9a and GLP methyltransferase activity in cellsThe xenograft antigen bound to Griffonia simplicifolia lectin 1-B(4). X-ray crystal structure of the complex and molecular dynamics characterization of the binding site.(NZ)CH...O Contacts assist crystallization of a ParB-like nucleaseStructure of the hypothetical protein PF0899 fromPyrococcus furiosusat 1.85 Å resolutionStructural basis of substrate-binding specificity of human arylamine N-acetyltransferasesBinding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector DomainIn situ proteolysis for protein crystallization and structure determinationAn intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 geneCrystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNEStructure and Function of a G-actin Sequestering Protein with a Vital Role in Malaria Oocyst Development inside the Mosquito VectorCrystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITYStructures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calciumComparative Structural Analysis of Human DEAD-Box RNA HelicasesPhosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin 1Structural and Histone Binding Ability Characterizations of Human PWWP DomainsPyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisCrystal structure of the Cys2His2-type zinc finger domain of human DPF2Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereusStructural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural DevelopmentStructural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4ECrystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteinsSequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lockHistone recognition by human malignant brain tumor domainsStructures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA DemethylationCrystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamidesRPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylationStructural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIPCrystal structure of DPF3b in complex with an acetylated histone peptide
P50
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P50
description
Canadian biotechnologist
@en
onderzoeker
@nl
name
Wolfram Tempel
@ast
Wolfram Tempel
@en
Wolfram Tempel
@es
Wolfram Tempel
@nl
Wolfram Tempel
@sl
type
label
Wolfram Tempel
@ast
Wolfram Tempel
@en
Wolfram Tempel
@es
Wolfram Tempel
@nl
Wolfram Tempel
@sl
prefLabel
Wolfram Tempel
@ast
Wolfram Tempel
@en
Wolfram Tempel
@es
Wolfram Tempel
@nl
Wolfram Tempel
@sl