9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo
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2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriDifferential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurineAntiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newbThe acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization.Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine on visna virus infection in lambs: a model for in vivo testing of candidate anti-human immunodeficiency virus drugs.Effect of tenofovir on nucleotidases and cytokines in HIV-1 target cells.Antiviral therapy for human immunodeficiency virus infectionsIn search of a selective antiviral chemotherapy.Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.Enantiomeric radiochemical synthesis of R and S (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid (FPMPA)Tenofovir: quo vadis anno 2012 (where is it going in the year 2012)?The acyclic nucleoside phosphonates (ANPs): Antonín Holý's legacy.Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates.A time-of-drug addition approach to target identification of antiviral compounds.Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonatesTransport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediatedNew developments in the chemotherapy of lentivirus (human immunodeficiency virus) infections: sensitivity/resistance of HIV-1 to non-nucleoside HIV-1-specific inhibitors.2'C-alkoxy and 2'-C-aryloxy derivatives of N-(2-phosphonomethoxyethyl)-purines and -pyrimidines: synthesis and biological activity.Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication.New therapeutic strategies in the treatment of hepatitis B virus infection.Discovery and Development of Tenofovir Disoproxil FumarateFrom adefovir to Atripla™ via tenofovir, Viread™ and Truvada™
P2860
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P2860
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@ast
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@en
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@nl
type
label
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@ast
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@en
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@nl
prefLabel
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@ast
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@en
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@nl
P2093
P2860
P50
P356
P1476
9-[(2RS)-3-fluoro-2-phosphonyl ...... al agents in vitro and in vivo
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.11.4961
P407
P577
1991-06-01T00:00:00Z