about
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replicationNovel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replicationAntiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization techniqueParticular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivoNew neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agentsSynthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent designSynthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridinesAntiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compoundsRapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compoundsSynthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain(+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral propertiesA rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frameAnti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replicationIn vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purineThe cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanineImidazothiadiazine dioxides: synthesis and antiviral activityNovel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosidesSynthesis and antiviral activity of 6-benzoyl-benzoxazolin-2-one and 6-benzoyl-benzothiazolin-2-one derivativesAntiviral activity of ganciclovir elaidic acid ester against herpesvirusesPotent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic baseStructure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the baseDifferential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurineThe lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applicationsA multi-targeted drug candidate with dual anti-HIV and anti-HSV activityThe Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal ApplicationsStudy of camelpox virus pathogenesis in athymic nude miceFurano pyrimidines as novel potent and selective anti-VZV agents.Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency.Systemic cidofovir in papillomatosis.Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain.Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility.Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir
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P50
description
hulumtues
@sq
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Robert Snoeck
@ast
Robert Snoeck
@br
Robert Snoeck
@co
Robert Snoeck
@cs
Robert Snoeck
@da
Robert Snoeck
@de
Robert Snoeck
@en
Robert Snoeck
@es
Robert Snoeck
@fr
Robert Snoeck
@id
type
label
Robert Snoeck
@ast
Robert Snoeck
@br
Robert Snoeck
@co
Robert Snoeck
@cs
Robert Snoeck
@da
Robert Snoeck
@de
Robert Snoeck
@en
Robert Snoeck
@es
Robert Snoeck
@fr
Robert Snoeck
@id
prefLabel
Robert Snoeck
@ast
Robert Snoeck
@br
Robert Snoeck
@co
Robert Snoeck
@cs
Robert Snoeck
@da
Robert Snoeck
@de
Robert Snoeck
@en
Robert Snoeck
@es
Robert Snoeck
@fr
Robert Snoeck
@id
P214
P1053
V-3867-2017
P106
P21
P214
P31
P3829
P496
0000-0002-7586-5434
P6023
P735
P7859
viaf-59861663