The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin
about
Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defenseTRAF family proteins link PKR with NF-kappa B activationThe C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.Molecular basis for PKR activation by PACT or dsRNAImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionPost-transcriptional Regulation of Immunological Responses through RiboclusteringAlphaherpesvirus Subversion of Stress-Induced Translational ArrestRegulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5ACytopathic and Noncytopathic Interferon Responses in Cells Expressing Hepatitis C Virus Subgenomic RepliconsProtein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infectionDouble-stranded RNA-dependent protein kinase regulates the motility of breast cancer cellsDouble-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infectionDouble-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasisQuantitative Proteomic Analysis of BHK-21 Cells Infected with Foot-and-Mouth Disease Virus Serotype Asia 1C114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase RLarge G3BP-induced granules trigger eIF2α phosphorylation.PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial loadThe protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in miceRole of PKR and Type I IFNs in viral control during primary and secondary infection.Stimuli-Responsive Mesoporous Silica NPs as Non-viral Dual siRNA/Chemotherapy Carriers for Triple Negative Breast Cancer.Sindbis viral vector induced apoptosis requires translational inhibition and signaling through Mcl-1 and Bak.Role of p58IPK in Endoplasmic Reticulum Stress-associated Apoptosis and InflammationdsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication.Stachybotrys chartarum, trichothecene mycotoxins, and damp building-related illness: new insights into a public health enigma.IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNAMechanisms of deoxynivalenol-induced gene expression and apoptosis.Inosine-containing RNA is a novel innate immune recognition element and reduces RSV infection.Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase RA Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ.Viruses, endoplasmic reticulum stress, and interferon responses.Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis.Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cellsA critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptorsRecombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances.The heat shock response and cytoprotection of the intestinal epithelium.Protein kinase R as mediator of the effects of interferon (IFN) gamma and tumor necrosis factor (TNF) alpha on normal and dysplastic hematopoiesis
P2860
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P2860
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@ast
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@en
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@nl
type
label
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@ast
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@en
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@nl
prefLabel
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@ast
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@en
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@nl
P2860
P3181
P356
P1433
P1476
The protein kinase PKR is requ ...... esponse to bacterial endotoxin
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/19.16.4292
P407
P577
2000-08-01T00:00:00Z