about
The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKRProtein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulationPhospholipid scramblase 1 potentiates the antiviral activity of interferonViral apoptosis is induced by IRF-3-mediated activation of BaxThe p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domainARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteinsARED 3.0: the large and diverse AU-rich transcriptome.Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and DiversityReplication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon ActivitiesHow cells respond to interferonsPKR; a sentinel kinase for cellular stressCharacterization of a 500-kb contig spanning the region between c-Ha-Ras and MUC2 on chromosome 11p15.5IL-10 regulates Aicda expression through miR-155Human Toll-like receptor 8 can be cool too: implications for foreign RNA sensingThe protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxinC114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase RApoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosisIdentification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arraysActivation of the interferon system by short-interfering RNAsA systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation.High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.Role of PKR and Type I IFNs in viral control during primary and secondary infection.Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.Rational design of immunostimulatory siRNAs.RNA-dependent protein kinase is required for alpha-1 interferon transgene-induced resistance to genital herpes simplex virus type 2.Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaBDefinition of the limits of the Wilms tumor locus on human chromosome 11p13.Differential expression of E-cadherin and beta catenin in primary and metastatic Wilms's tumoursCharacterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase.Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L.Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation.Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.Expression of IFITM1 in chronic myeloid leukemia patients.Alphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.Signal integration via PKR.OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures.
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Bryan R Williams
@ast
Bryan R Williams
@en
Bryan R Williams
@es
Bryan R Williams
@nl
Bryan R Williams
@sl
type
label
Bryan R Williams
@ast
Bryan R Williams
@en
Bryan R Williams
@es
Bryan R Williams
@nl
Bryan R Williams
@sl
prefLabel
Bryan R Williams
@ast
Bryan R Williams
@en
Bryan R Williams
@es
Bryan R Williams
@nl
Bryan R Williams
@sl
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P106
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P496
0000-0002-4969-1151