Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
about
Comprehensive identification of conditionally essential genes in mycobacteria1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)Mechanism of thioamide drug action against tuberculosis and leprosyStrategies for potentiation of ethionamide and folate antagonists against Mycobacterium tuberculosisThe mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kineticsTriclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosisStructural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligandsA new dehydratase conferring innate resistance to thiacetazone and intra-amoebal survival of Mycobacterium smegmatisUnique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosisThe antituberculosis drug ethionamide is activated by a flavoprotein monooxygenaseThe molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosisThiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteriaSynthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analoguesEthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targetsThe prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenaseideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress responseMycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosisIdentification of new drug targets and resistance mechanisms in Mycobacterium tuberculosisWhole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patientsElucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencingAn ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid compositionApplication of quantitative second-line drug susceptibility testing at a multidrug-resistant tuberculosis hospital in Tanzania.Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis.Transposition of Tn5367 in Mycobacterium marinum, using a conditionally recombinant mycobacteriophageCompounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1).A synthetic mammalian gene circuit reveals antituberculosis compounds.High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.EthA/R-Independent Killing of Mycobacterium tuberculosis by Ethionamide.A joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learnt.The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South AfricaFragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.Rate and amplification of drug resistance among previously-treated patients with tuberculosis in Kampala, UgandaCyclic di-GMP regulates Mycobacterium tuberculosis resistance to ethionamideNoncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids.ethA, inhA, and katG loci of ethionamide-resistant clinical Mycobacterium tuberculosis isolatesExtensively Drug-Resistant Tuberculosis: A Sign of the Times and an Impetus for Antimicrobial Discovery.Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosisMolecular investigation of resistance to the antituberculous drug ethionamide in multidrug-resistant clinical isolates of Mycobacterium tuberculosisBioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases.Current status and future development of antitubercular chemotherapy.
P2860
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P2860
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@ast
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@en
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@nl
type
label
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@ast
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@en
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@nl
prefLabel
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@ast
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@en
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@nl
P2093
P2860
P356
P1476
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.17.9677
P407
P577
2000-08-01T00:00:00Z