Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production
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Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysisCardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxiaIncreased hepatic fructose 2,6-bisphosphate after an oral glucose load does not affect gluconeogenesis.Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistanceMB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice.Gene expression profile analysis of type 2 diabetic mouse liver.Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity.Cell therapies for type 1 diabetes mellitus.Probing lactate dehydrogenase activity in tumors by measuring hydrogen/deuterium exchange in hyperpolarized l-[1-(13)C,U-(2)H]lactate.Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response.Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity.Liver glucokinase: An overview on the regulatory mechanisms of its activity.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Liver Glucokinase(A456V) Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase.Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism.Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1.Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes.Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice using in vivo (13)C NMR measurements of hepatic carbohydrate metabolism.Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons.Functional characterization of muscle fibres from patients with chronic fatigue syndrome: case-control study.Characterization of hepatic fatty acids in mice with reduced liver fat by ultra-short echo time (1)H-MRS at 14.1 T in vivo.CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.
P2860
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P2860
Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production
description
2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@ast
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@en
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@nl
type
label
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@ast
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@en
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@nl
prefLabel
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@ast
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@en
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@nl
P2093
P2860
P921
P356
P1476
Overexpression of 6-phosphofru ...... ing hepatic glucose production
@en
P2093
P2860
P356
10.1172/JCI11103
P407
P577
2001-01-01T00:00:00Z